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Renal Recovery After PEEP Weaning in ARDS (RE2SDRA)

Renal Recovery After PEEP Weaning in ARDS

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06754787
Acronym
RE2SDRA
Enrollment
120
Registered
2025-01-01
Start date
2024-03-21
Completion date
2024-08-01
Last updated
2025-01-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AKI - Acute Kidney Injury, ARDS (Acute Respiratory Distress Syndrome)

Brief summary

The purpose of the study is to investigate renal recovery in ARDS after PEEP weaning. The primary outcome was the variation of the hourly urine output (HUO), 48 h after PEEP weaning. Secondary outcomes were the need for RRT and mortality. Two groups were defined depending wether hourly urine output was greater or lower than 0.35 mL/kg/h.

Interventions

None listed

Sponsors

University Hospital, Brest
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
15 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* intubated for more than 48 hours, exposed to a PEEP≥ 8 cmH20

Exclusion criteria

* chronic end-stage renal disease on admission * refusal to participate * non-opposition could not be obtained from themselves or their trusted support person in the event of incapacity * under legal protection.

Design outcomes

Primary

MeasureTime frameDescription
Variation of the hourly urine output on day 2 after PEEP weaningFrom enrollement to day 2 after PEEP weaningVariation of the hourly urine output on day 2 after PEEP weaning

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026