Myasthenia Gravis
Conditions
Keywords
Myasthenia Gravis, traditional Chinese medicine
Brief summary
Myasthenia gravis primarily results from neuromuscular junction dysfunction and damage, leading to chronic muscle weakness. While combined traditional and Western medicine treatments are now common, TCM tongue diagnosis remains a simple and practical clinical method. However, results can vary among different practitioners. Therefore, you are interested in using scientific methods to compare TCM tongue diagnosis images between patients with myasthenia gravis and healthy individuals to aid in diagnosis.
Detailed description
In Taiwan, the prevalence of severe myasthenia gravis is approximately 14 per 100,000 people, with an incidence rate of about 2 per 100,000 people. Currently, combined traditional and Western medicine treatments are very popular. In Traditional Chinese Medicine (TCM), tongue diagnosis is a simple and practical clinical method, focusing on aspects such as the tongue body, coating, color, and sublingual veins. Clinical evaluation often relies on the experience and knowledge of TCM practitioners, which can be influenced by subjective factors like diagnostic skills. As a result, findings may vary depending on the observer. To improve diagnostic accuracy, using scientific methods to support TCM tongue diagnosis can provide more precise information for practitioners and enhance the clinical application value of tongue diagnosis in TCM.
Interventions
DEVICEHeart Rate Variability,HRV - ANSWatch
Please have the participant lie down and rest for 10 minutes, and remove any metallic items from their body. Next, put on the wrist-worn monitor, and avoid moving during the monitoring process. The device will emit a sound when the monitoring session is complete.
DEVICETraditional Chinese Medicine Tongue Imaging
Use a camera to capture images of the tongue, and then have a Traditional Chinese Medicine (TCM) practitioner perform the diagnosis based on these images.
Sponsors
Yi Ting Yeh
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Diagnosed with myasthenia gravis by a physician. 2. Able to understand and communicate in Mandarin and Taiwanese. 3. Cognitively alert and without a diagnosis of psychiatric disorders. 4. Willing to undergo tongue imaging and instrument measurements.
Exclusion criteria
1. Patients with severe organ diseases. 2. Hearing loss patients who are unable to complete the questionnaire. 3. Patients with aphasia who are unable to complete the questionnaire. 4. Have eaten food or drinks that can easily contaminate tongue coating within 2 hours.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| What are the differences in tongue diagnosis in traditional Chinese medicine between the disease group and the healthy population? | 2025/01/18 (4th week) | Using a camera to capture images of the tongue, traditional Chinese medicine practitioners were invited to evaluate the tongue photographs. After organizing the data, a comparison between the two groups was conducted in the fourth week. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Observe the differences in physical constitution and tongue diagnosis between patients with myasthenia and healthy people. | 2025/01/18 (4th week) | The disease group and the control group were asked to complete the Traditional Chinese Medicine Constitution Questionnaire (TCMCQ) separately. After organizing the data, statistical analysis was conducted in the fourth week. |
Countries
Taiwan
Contacts
CONTACTYI TIMG YEH
Outcome results
None listed