Hemostasis
Conditions
Brief summary
The PFA (platelet function analysis) test is prescribed for the exploration of primary hemostasis and the study of platelet-willebrand factor interaction. It is performed using citrated blood, with technical difficulties and frequent alarms that may be linked to the choice of anticoagulant (citrate). It is proposed to compare the results obtained with a conventional citrate tube and a BAPA tube, which is an anticoagulant used in clinical research and which blocks coagulation by another mechanism that would have less impact on blood platelets.
Interventions
BIOLOGICALSampling of 3 additional BAPA tubes
the 3 additional tubes will be taken at the same time as the blood sample taken for the routine PFA test
Sponsors
Centre Hospitalier Universitaire Dijon
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Person having given their non-opposition * Person of legal age * Person receiving a haemostasis consultation at the haemophilia and haemorrhagic diseases treatment center followed by a blood sample with a PFA test prescribed by the doctor (the test is not added for the study).
Exclusion criteria
* persons under legal protection (curatorship, guardianship) * persons subject to a court protection order * pregnant, parturient or breast-feeding women * adult incapable or unable to give consent * minor
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Occlusion time measurement | at baseline | Measurement of the occlusion times of the 2 cartridges (collagen/ADP and collagen/epinephrine) with the classic 0.109M citrate tube and the BAPA tube, with any PLC alarms and observation of the stained blood smears. |
Countries
France
Contacts
Primary ContactEmmanuel De Maistre
Outcome results
None listed