Myopia
Conditions
Brief summary
examines the influence of lens-induced defocus on contrast sensitivity-a crucial aspect of visual performance.Each participant experiences both positive and negative defocus through different lenses, with measurements taken for contrast sensitivity using the Pelli-Robson chart. Outcomes are evaluated at baseline, 2 weeks, and 4 weeks to understand the effect of defocus over time.
Detailed description
Additional data on symptoms like visual fatigue and computer vision syndrome are gathered using the Visual Fatigue Questionnaire (VFQ) and the Computer Vision Syndrome Questionnaire (CVS-Q), respectively. This study's findings could be instrumental in refining optical treatments, offering insights into how defocus impacts visual function across refractive conditions. Results may ultimately benefit optometric practices by guiding lens prescriptions for improved contrast sensitivity and quality of life for myopic and non-myopic individuals alike.
Interventions
DIAGNOSTIC_TESTPositive Lens-Induced Defocus Using Spectacle Lenses (+2.00 D) for Myopic Participants
Intervention Description: This group will be exposed to positive defocus induced by +2.00 D spectacle lenses. The lenses are designed to create optical blur to evaluate the effects on contrast sensitivity and visual fatigue. Measurements will be conducted at baseline, 2 weeks, and 4 weeks after exposure to assess changes in visual function.
DIAGNOSTIC_TESTNegative Lens-Induced Defocus Using Spectacle Lenses (-2.00 D) for Myopic Participants
Intervention Description: This group will be exposed to negative defocus induced by -2.00 D spectacle lenses. The induced defocus will allow for the evaluation of its impact on contrast sensitivity and visual fatigue. Assessments will be carried out at baseline, 2 weeks, and 4 weeks.
COMBINATION_PRODUCTPositive Lens-Induced Defocus Using Spectacle Lenses (+2.00 D) for Non-Myopic Participants
ntervention Description: This group will undergo positive defocus using +2.00 D spectacle lenses. The intervention aims to examine the effect of induced defocus on contrast sensitivity and visual fatigue in non-myopic participants. Data will be collected at baseline, 2 weeks, and 4 weeks.
COMBINATION_PRODUCTNegative Lens-Induced Defocus Using Spectacle Lenses (-2.00 D) for Non-Myopic Participants
Intervention Description: This group will experience negative defocus induced by -2.00 D spectacle lenses. The purpose is to evaluate how negative lens-induced defocus affects contrast sensitivity and visual fatigue in non-myopic participants. Measurements will be taken at baseline, 2 weeks, and 4 weeks.
Sponsors
Superior University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Adults aged 18 to 50 years. * Participants with a confirmed diagnosis of myopia or non-myopia. * Best corrected visual acuity of 20/30 or better. * No history of ocular surgery or significant ocular disease. * Informed consent was obtained.
Exclusion criteria
* Individuals with a history of systemic diseases affecting vision (e.g., diabetes, hypertension). * Presence of binocular vision anomalies or strabismus. * Pregnant or nursing women. * Any current use of medications affecting visual function (e.g., medications causing visual side effects).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Contrast Sensitivity | 12 Months | Measured with the Pelli-Robson Contrast Sensitivity Chart, capturing changes in participants' ability to detect low-contrast visual stimuli under defocus conditions. |
| Visual Fatigue | 12 months | Evaluated with the Visual Fatigue Questionnaire (VFQ) and Computer Vision Syndrome assessing symptoms like eye strain, discomfort, and fatigue following lens-induced defocus. |
Countries
Pakistan
Outcome results
None listed