Irrigation Solution, Periapical Diseases, Photodynamic Therapy (PDT), Postoperative Dental Pain
Conditions
Keywords
postoperative pain, endodontics, root canal irrigation, curcumin, photodynamic therapy
Brief summary
In endodontics, various irrigation solutions are used to achieve antibacterial efficacy within the root canal. The antibacterial effect of curcumin-containing root canal solutions, when combined with photodynamic therapy, has been demonstrated in several studies. However, no research has specifically examined their effect on postoperative pain. The aim of this study is to investigate the impact of using a curcumin solution in combination with photodynamic therapy as the final irrigation solution on postoperative pain.
Detailed description
Fifty patients were randomly assigned to two groups using a web-based program, according to the selected final irrigation procedure: curcumin-photodynamic therapy or a control group (routine root canal final irrigation with NaOCl and EDTA). The teeth will be isolated with a rubber dam, and access cavities will be created. After root canal preparation, the final irrigation procedure will be performed. Root canal treatments will then be completed, and the patients' postoperative pain levels will be recorded using follow-up forms.
Interventions
OTHERCurcumin with photodynamic thearpy
root canals will irrigated with final irrigation procedure: curcumin+photodynamic therapy. The teeth will be isolated with a rubber dam, and an access cavity will be created. After root canal preparation, the final irrigation procedure will be performed. Root canal treatments will be completed, and the patients' postoperative pain levels will be recorded using follow-up forms.
OTHERControl group
root canals will irrigated with routine root canal final irrigation with NaOCl and EDTA. The teeth will be isolated with a rubber dam, and an access cavity will be created. After root canal preparation, the final irrigation procedure will be performed. Root canal treatments will be completed, and the patients' postoperative pain levels will be recorded using follow-up forms.
Sponsors
Ataturk University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Intervention model description
Randomized Clinical Trial
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy patients with aged between 18-60. * Incisor, canine, and premolar teeth that had previously undergone root canal treatment * Incisor, canine, and premolar teeth with a diagnosis of chronic apical abscess or asymptomatic apical periodontitis * teeth with only 1 root canal * the patients had not used any antibiotics for 3 months before treatment
Exclusion criteria
* the presence of a root fracture * teeth with any swelling * ankyloses, * periodontal pockets deeper than 4 mm. * teeth which a rubber dam could not be performed * patients with allergy to ibuprofen or ciprofloxacin were also excluded.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| postoperative pain levels | one week | postoperative pain levels will be describe using the visual analog scale (VAS). The VAS was classified using the following scale \[15\]: no pain (0); mild pain (1-3); moderate pain (4-6), and severe pain (7-10). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| dependent variables-sex | one week | The patients' genders (female or male) will be recorded, and their relationship with postoperative pain will be statistically analyzed. |
| dependent variable-age | one week | The patients' ages will be recorded as numbers, and their relationship with postoperative pain will be statistically analyzed. |
| dependent variables-teeth number | one week | The patients' tooth numbers will be recorded, and their relationship with postoperative pain will be statistically analyzed. |
| dependent variables-smoking habit | one week | The patients' smoking habits will be recorded as either yes or no, and their relationship with postoperative pain will be statistically analyzed. |
Countries
Turkey (Türkiye)
Contacts
Primary ContactMeltem Sumbullu, DDS
Backup ContactTuğçe Sönmez, DDS
Outcome results
None listed