Pain After Photorefractive Keratectomy, VAS Will be Used to Assess Pain Postoperative
Conditions
Brief summary
The current study aims at assessing the efficacy and safety of oral Gabapentin alone versus Diclofenac Potassium drugs for postoperative analgesia in patients undergoing surface ablation.
Detailed description
To estimate the analgesic effect and pain severity after surface ablation with oral Gabapentin intake in comparison with Diclofenac Potassium, where Gabapentin could be a better analgesic medication after surface ablation
Interventions
DRUGGiving post photorefractive keratectomy for pain relief
We plan to conduct a randomized prospective study to assess the efficacy and safety of oral Gabapentin versus oral Diclofenac Potassium for postoperative analgesia in adults undergoing surface ablation. The first group will be given gabapentin orally in a dose of 300mg Tid for 72 hours and the second group will be given oral diclofenac potassium 50mg Tid for 72 hours. The drugs will be administered starting from the first day postoperative.
Sponsors
Research Institute of Ophthalmology, Egypt
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* patients over 18 years old * preoperative stable refraction for at least one-year, * normal corneal tomography with expected postoperative flat K reading not less than 38D, and postoperative residual stromal bed not less than 350 μm.
Exclusion criteria
* Patients with preoperative corrected distance visual acuity (CDVA) of worse than 20/30 * amblyopic patients, * patients with a history of previous ocular surgeries, * herpetic eye infection, or corneal dystrophies. * Patients with other ocular conditions e.g. uveal or retinal diseases, and glaucoma * Diabetics, * Hypertensives, * Kidney problems, * breathing problems * Adults older than 65 years. * Previous allergy or adverse reaction to the used drugs. * History of drug abuse or alcohol abuse problems * History of mood problems, depression suicidal thoughts or behavior
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative Pain intensity will be evaluated with the visual analog scale (VAS) after surgery up to 72 hours. | 72 hours postoperative | pain assessment using Visual Analogue Scale |
Countries
Egypt
Contacts
Primary ContactDina Moustafa M Ali, MD
Backup ContactMohamed Tarek Ahmed El- Naggar, MD- FRCS
Outcome results
None listed