Cataract
Conditions
Brief summary
Using Psychophysics Methods for Quantitative Assessment of Sensory Binocular Imbalance After Cataract Surgery
Detailed description
Using binocular phase combination paradigms and binocular rivalry paradigms to quantitatively assess the degree of sensory binocular imbalance in patients following cataract surgery, investigating the relationship between unilateral and bilateral cataracts in children and varying severities of cataracts in adults with respect to sensory ocular dominance, and forecasting the postoperative quality of life for patients.
Interventions
None listed
Sponsors
Wenzhou Medical University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
6 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
1. Ages between 6 and 90 years old, and the individual or legal guardian is capable of understanding and voluntarily signing an informed consent form; 2. No history of ocular trauma or intraocular surgery, no physical or medical treatments have been undergone, and the clinical diagnosis in the medical records is age-related, congenital, or developmental cataract patients; 3. Best-corrected visual acuity in both eyes is greater than 0.8 before the study, fusion ability is normal as checked by Worth's 4-dot test, and at least 1 month has passed since the last surgery; 4. Good communication skills and the ability to understand and grasp the trial; 5. No significant contraindications to surgery found in preoperative systemic and ocular examinations.
Exclusion criteria
1. Patients with traumatic or complex cataracts; 2. Those diagnosed with glaucoma before or after surgery; 3. Individuals with a history of intraocular surgery (such as vitrectomy) or laser treatment; 4. Exclude those with severe ocular comorbidities (including microphthalmia, aphakia, anterior segment dysgenesis, uveitis, optic nerve dysplasia, retinopathy of prematurity, congenital glaucoma, etc.) and severe systemic comorbidities (including syndromes affecting connective tissue function, such as Marfan syndrome, homocystinuria, or Down syndrome, severe birth defects, and epilepsy); 5. Any systemic diseases related to the eyes, such as rheumatic immune diseases; 6. Those with surgical records indicating any severe intraoperative complications during cataract surgery; 7. Individuals who cannot cooperate with the examination.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Perceptual Phase | Each subject undergoes a one-time examination, which lasts for about a year. Each subject's participation in this clinical study will take approximately 0.5 hour. | The perceptual phase when the interocular contrast between the two eyes is 1. |
| Ocular Dominance Index (ODI) | Each subject undergoes a one-time examination, which lasts for about a year. Each subject's participation in this clinical study will take approximately 0.5 hour. | The ratio of the total time spent by the observer reporting complete dominance of visual stimuli presented to the dominant or non-dominant eye. |
Countries
China
Outcome results
None listed