Adenomyosis of Uterus
Conditions
Brief summary
This study aims to compare the safety and efficacy of segmental power adjustment combined with uterine cavity hydro-isolation in microwave ablation of adenomyosis
Interventions
PROCEDUREPeritoneal combined with intrauterine water isolation
On the basis of the conventional peritoneal water isolation group, the improved technology group added additional intrauterine water isolation, and continued to inject ice saline to separate the endometrium on both sides.
PROCEDUREPeritoneal water isolation
Transabdominal injection of saline into the abdominal cavity to achieve complete separation of the uterus from the surrounding organs and structures
Sponsors
Peking University Aerospace Center Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
1. UFs or AM diagnosed by pathology and ultrasound； 2. Relevant symptoms such asabnormal uterine bleeding, secondary anemia, progressive dysmenorrhea and enlargement of the uterus； 3. Voluntarily undergo MWA； 4. a confirmed available safe transabdominal puncture path；
Exclusion criteria
1. Pregnancy or malignancy； 2. Severe and uncorrectable coagulation disorders； 3. Severe cardiac, liver, and renal dysfunction； 4. Anesthesia allergy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The rates of endometrial injury | From enrollment to the end of treatment at 3 months | Observe the differences in the rates of endometrial injury between two groups |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The reduction rate of adenomyosis volume | From enrollment to the end of treatment at 1 year | Observe the reduction rate of adenomyosis volume between two groups |
| complication | From enrollment to the end of treatment at 1 year | The complication rate between the two groups was compared |
Countries
China
Outcome results
None listed