Accuracy of Automatic Contusion Volume Scanning for Predicting the Incidence of Pneumonia in Patients With Thoracic Trauma

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06750822

Acronym

RESOLUTION

Enrollment

486

Registered

2024-12-27

Start date

2024-05-01

Completion date

2024-12-01

Last updated

2024-12-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia, Thoracic Trauma

Keywords

AAST, AISThorax, Pneumonia, trauma

Brief summary

The goal of this retrospective observational study is to evaluate the diagnostic accuracy of pulmonary contusion volume in predicting early pneumonia in patients with thoracic trauma. The primary question we aim to answer is: What is the diagnostic accuracy of pulmonary contusion volume in predicting pneumonia within 7 days post-trauma? Moreover, we aim to explore which is the overlap between the contused segments and those developing pneumonia. Finally, we aim to explore relevant differences in radiomic features between contused segments that developed pneumonia.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Admission to the ED for trauma as primary diagnosis * Whole-body contrast CT scan performed within 6 hours from admission

Exclusion criteria

* Age \<18 years

Design outcomes

Primary

Measure	Time frame	Description
7d-pneumonia	7 days	Pneumonia appearing within 7 days from trauma, defined as: • New or worsening pulmonary infiltrates plus ≥ 2 of the following: * Body temperature ≥ 38°C or ≤ 35°C * White Blood Cell (WBC) count \> 12,000 or \< 4,000 cells/mL or presence of immature granulocytes in the blood sample * Purulent sputum * Worsening pulmonary oxygenation, defined as a decline in the PaO2/FiO2 ratio

Countries

Italy

Outcome results