LCx Occlusion STEMI, STEMI
Conditions
Keywords
LCx occlusion STEMI
Brief summary
To assess procedural success and short term clinical outcomes of primary PCI to isolated LCx acute occlusion.
Detailed description
ST-segment elevation myocardial infarction (STEMI) involving acute occlusion of the left circumflex (LCx) coronary artery represent only 14-21% of STEMIs LCx acute occlusion may be difficult to be diagnosed . Only 50% of patients with LCx occlusion exhibited ST segment elevation during the acute phase, 38% showed no ST segment changes, while 15% presented with isolated ST segment depression This may lead to delay in transfer to cath lab, delay in reperfusion therapy and consequently loss of more myocytes and more major adverse cardiovascular events (MACE) . Due to relative rare occurrence of isolated LCx coronary artery occlusion, little is known in literature about the clinical outcomes of isolated LCx occlusion , so we will conduct a retrospective observational study in our tertiary primary percutaneous coronary intervention (PCI) center to detect the incidence , procedural and clinical outcomes after 6 months of patients who had isolated LCx acute occlusion and underwent primary PCI.
Interventions
None listed
Sponsors
Assiut University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients presented to Assiut University heart hospital with STEMI who underwent primary PCI that revealed isolated LCx acute occlusion (single culprit artery) between January 2018 to January 2025 will be included.
Exclusion criteria
-Patients with cardiogenic shock, NYHA class III-IV and multivessel coronary artery disease will be excluded.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Complications of PPCI to LCx occlusion | 6 months | defined as angiographic success without in-hospital complications). Angiographic success (defined as in-stent residual stenosis ≤30% without serious angiographic complications (severe coronary dissection impairing flow \[type D-F\], perforation, abrupt closure or no reflow) . |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Long follow up of outcomes of PPCI of LCx outcomes | 6 months | The secondary endpoint will be assessment of MACE at 6 months following the index procedure. MACE ( defined as the composite of all-cause mortality, target lesion revascularization, stent thrombosis, documented atrial fibrillation and development of heart failure). |
Contacts
Primary ContactEsraa Gamal Mohammed, Master student
Outcome results
None listed