A Comparative Analysis of Ultrasound's Accuracy in Diagnosing HC Using Histopathology as Gold Standard

A Comparative Analysis of Ultrasound's Accuracy in Diagnosing Hepatocellular Carcinoma Using Histopathology as Gold Standard

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06748755

Enrollment

Registered

2024-12-27

Start date

2024-03-01

Completion date

2025-02-20

Last updated

2024-12-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular Carcinoma

Brief summary

The study aims to evaluate the accuracy of ultrasound in diagnosing hepatocellular carcinoma (HCC), using histopathology as the gold standard. It addresses HCC's high global incidence and the utility of ultrasound as a non-invasive, cost-effective screening tool. Despite ultrasound's accessibility, its diagnostic limitations necessitate further investigation to improve clinical outcomes.

Interventions

RADIATIONGroup 1

To determine the sensitivity of ultrasound in detecting HCC

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Inclusion criteria

* Clinically suspected liver cancer patients undergoing ultrasound examination. * Patients undergoing histopathological examination (liver biopsy or resection) for definitive diagnosis.

Exclusion criteria

\- Patients with history of liver cancer treatment or inadequate data.

Design outcomes

Primary

Measure	Time frame	Description
ultrasound	12 Months	Sensitivity and Specificity analysis of Ultrasound as diagnostic tool, with histopathology as gold standard.

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026