Diabetic Ketoacidosis
Conditions
Keywords
serum Ferritin, Diabetic Ketoacidosis
Brief summary
the aim of this study is to: evaluate the association between serum ferritin levels and the clinical presentation and short-term prognosis of patients with DKA. Specifically, the correlation between its level and the severity of DKA at presentation and determine its prognostic value in predicting short-term outcomes.
Detailed description
Ferritin studies and correlation to acute events like stroke or Mi was done before, however some studies have found a correlation with the degree and prognosis of these diseases and others not. However no study was tried on DKA patients before so the investigators are trying to find if Ferritin would have a relation with patients of Dka and could be used as a prognostic tool (for example we found in this study when level is less than 200 patients mostly has good prognosis) this is just an example or (serrum ferritin turned out to be irrelevant to DKA prognosis as patients would have good prognosis despite number value) and this will be in selected patients according to criteria to exclude any chronic condition in the investigators hospital care units.
Interventions
None listed
Sponsors
Sohag University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
\- All patients with DKA : 1. Adult Aged 18 years old or older . 2. Type 1 DM , type 2 DM 3. Diagnosis of DKA based on the American Diabetes Association criteria: blood glucose \>250 mg/dL, arterial pH \<7.3, serum bicarbonate \<18 mEq/L,
Exclusion criteria
1. Patients age less than 18 years old 2. Iron deficiency anemia and iron overload 3. Chronic Inflammatory Diseases: Conditions such as rheumatoid arthritis, systemic lupus erythematosus, and inflammatory bowel disease 4. Acute and chronic infections, including bacterial, viral, and fungal infections 5. Pt presented with other acute complication (MI,stroke) 6. CKD patients 7. Patients with chronic liver diseases 8. Patients with malignancy 9. Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| evaluate the association between serum ferritin levels and the clinical presentation and short-term prognosis of patients with DKA. Specifically, the correlation between its level and the severity of DKA at presentation and determine its prognostic value | Through the study completion, an average of 1 year |
Countries
Egypt
Contacts
Primary ContactJoseph Medhat Sobhy, resident in internal medicine
Backup ContactMarium Medhat Sobhy, resident in opthalmology
Outcome results
None listed