HIV Database (DBHIV)-Establishment of a Database of HIV Patients

Database HIV (DBHIV)-Costituzione di un Database di Pazienti HIV.

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06747754

Acronym

HIVDB

Enrollment

4900

Registered

2024-12-24

Start date

2025-01-01

Completion date

2030-12-31

Last updated

2024-12-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV Infections

Brief summary

In Italy, there are over 90,000 patients with HIV-1 infection on antiretroviral therapy (ART). The availability of different classes of antiretroviral drugs (nucleoside and non-nucleoside reverse transcriptase inhibitors (NRTIs, NNRTIs), protease inhibitors (PIs), integrase inhibitors (INSTIs) and viral entry inhibitors (IEs) that act in different phases of the HIV life cycle, together with careful patient management, has allowed us to obtain long-lasting therapeutic efficacy in the vast majority of Italian patients, making this infection a chronic disease.The introduction of combination antiretroviral therapy (cART) has completely revolutionized the management of HIV-positive patients, drastically reducing HIV-associated mortality and morbidity. In fact, the course of HIV infection has transformed into a chronic disease, and the number of HIV-infected patients over 50 years of age has increased significantly and the number of elderly subjects is progressively increasing. Furthermore, HIV infection seems to accelerate the aging process, causing immune system dysfunction, excess oxidative stress and increased inflammatory processes (inflammaging).

Interventions

OTHEREstablishment of a Database of HIV Patients

Establishment of a database that allows for systematic and continuous collection of data relating to clinical, laboratory and treatment characteristics of patients with HIV-1 for research purposes.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Age \>18 years * Patients with chronic HIV infection (certified by a positive test for the detection of anti-HIV antibodies) * Ability to sign the informed consent or signature of the declaration in lieu of consent in the case of deceased patients

Exclusion criteria

* lack of willingness to provide free and informed consent.

Design outcomes

Primary

Measure	Time frame	Description
Establishment of a database	5 years	Establishment of a database that allows for systematic and continuous collection of data relating to clinical, laboratory and treatment characteristics of patients with HIV-1 for research purposes.

Countries

Italy

Contacts

Primary ContactCarlo Torti, Prof

carlo.torti@policlinicogemelli.it00390630154945

Backup ContactFrancesca Lombardi, Dr

francesca.lombardi@policlinicogemelli.it

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026