Joint Arthroplasty, Osteoarthritis of the Hip or Knee
Conditions
Brief summary
The goal of this clinical trial is to learn if vitamin D supplementation affects postoperative rehabilitation in osteoarthritis patients who underwent joint arthroplasty. The main questions it aims to answer are: Does oral vitamin D supplementation for a period of time after joint arthroplasty affect the postoperative recovery speed in patients who have vitamin D deficiency? Does oral vitamin D supplementation after joint arthroplasty affect the long-term recovery of joint functions in patients who have vitamin D deficiency? Participants will: Take vitamin D oral supplement every day for 3 months. Visit the clinic in 1, 3, 6, 12 months after joint replacement surgery for checkups and tests.
Interventions
DRUGVitamin D
Vitamin D oral supplementation
Sponsors
Yiwu Fuyuan Private Hospital
Hangzhou Xiaoshan Traditional Chinese Orthopedic Hospital
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
60 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
1. Vitamin D deficiency (blood 25-hydroxyvitamin D value \< 20ng/ml); 2. Meeting the diagnostic criteria for hip or knee osteoarthritis; 3. Planning to undergo hip or knee arthroplasty after clinical assessment;
Exclusion criteria
1\. Having other diseases that could cause damage to the bone or cartilage structure of the hip or knee, such as trauma, joint infection, congenital joint malformation, and systemic diseases such as rheumatoid arthritis and gout.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Knee joint function | From enrollment to the end of treatment at 1 year | Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Pain ranging from 0 to 20 points; stiffness, 0 to 8 points; and physical function, 0 to 68 points. Higher scores represent worse pain, stiffness, and functional limitations. |
| Hip joint function | From enrollment to the end of treatment at 1 year | Harris Hip Score. The maximum score possible is 100. Results can be interpreted with the following: \<70 = poor result; 70-80 = fair, 80-90 = good, and 90-100 = excellent. |
| Muscle strength | From enrollment to the end of treatment at 1 year | Using portable muscle strength tester to measure flexor and extensor muscle strength of knee or hip joint |
Countries
China
Contacts
Primary ContactXiang Zhao, MD
Backup ContactZihao Qu, MD
Outcome results
None listed