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Evolution of the Relationship Between Central and Peripheral Arterial Wave Velocities as a Function of Age

Evolution of the Relationship Between Central and Peripheral Arterial Wave Velocities as a Function of Age

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06742775
Acronym
EvolVOAge
Enrollment
60
Registered
2024-12-19
Start date
2025-02-28
Completion date
2027-02-28
Last updated
2024-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aging, Diagnostic Techniques, Cardiovascular

Keywords

photoplethysmography, electrocardiography, inductive plethysmography, Pulse Wave Velocity

Brief summary

Acquisition of synchronized cardiovascular signals from non-invasive measurements (ECG, photoplethysmography pulse sensors, inductance plethysmography) in healthy volunteers aged from 18 to 75, during spontaneous ventilation with apneas (20 seconds) for a total acquisition time of 30 minutes.

Interventions

OTHERphysiological signal acquisitions

Subjects will be fitted with non-intrusive devices. In a semi-recumbent position, they will be asked to perform * 10 minutes of resting breathing * 10 cycles consisting of a 20-second apnea, to be performed at the end of inspiration, and 1 minute 40 of breathing (100 seconds). This single participation session will last a total of one hour for the volunteer (equipment, recording, de-equipping), including 30 minutes of acquisition.

Sponsors

University Grenoble Alps
CollaboratorOTHER
University Hospital, Grenoble
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes

Inclusion criteria

* Men and women between 18 and 75 years of age * No acute cardiovascular pathologies less than 2 years old, * No chronic cardiovascular pathologies. * Stature compatible with the use of the plethysmography T-shirt. * Person affiliated to a social security scheme or beneficiary of such a scheme * Signed informed consent form

Exclusion criteria

* Persons covered by articles L1121-5 to L1121-8 of the CSP (corresponding to all protected persons: pregnant women, parturients, nursing mothers, persons deprived of their liberty by judicial or administrative decision, persons under psychiatric care under articles L. 3212-1 and L. 3213-1 who are not covered by the provisions of article L. 1121-8, persons admitted to a health or social establishment for purposes other than research, minors, persons under legal protection or unable to express their consent). * Personnel with a hierarchical link to the principal investigator * Subjects excluded from another study,

Design outcomes

Primary

MeasureTime frameDescription
Electrocardiogram1 houracquisition of ECG signals
Photoplethysmography1 houracquisition of peripheral and central photoplethysmographic signals with radial, brachial, carotid and femoral sensors
inductive plethysmography1 houracquisition of abdominal and thoracic section variations with an inductive plethysmographic vest

Secondary

MeasureTime frameDescription
link between peripheral and central pulse wave velocity1 hourAssesment of the link between peripheral and central vascular function with statistical analysis (Linear regression, Bland and Altman test)

Countries

France

Contacts

Primary ContactStéphane TANGUY
stephane.tanguy@univ-grenoble-alpes.fr+33476637117

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026