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Accuracy and External Validation of mREMS in Road Traffic Injuries

Can the Modified Rapid Emergency Medicine Score (mREMS) Predict Trauma Patients' Outcomes in a Deteriorated Health System After Decades of Conflict?

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06740409
Acronym
AVE-MREMS
Enrollment
292
Registered
2024-12-18
Start date
2025-03-01
Completion date
2026-01-15
Last updated
2026-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trauma

Keywords

MREMS

Brief summary

The goal of this prospective observational study is to assess the accuracy and external validation of the Modified Rapid Emergency Medicine Score (mREMS) in predicting outcomes for patients with road traffic injuries (RTIs) admitted to the emergency department of a hospital in Baghdad. The main questions it aims to answer are: How accurate is the mREMS in predicting the prognosis of road traffic injury patients? Does the mREMS provide reliable predictive value in a local context, specifically in Baghdad? Participants will: Be assessed using the mREMS upon admission to the emergency department. Have their clinical outcomes, including mortality, need for surgery, and length of stay, monitored throughout their hospital stay.

Detailed description

Road traffic injuries (RTIs) are one of the leading causes of morbidity and mortality globally, disproportionately affecting low- and middle-income countries such as Iraq. Accurate and standardized clinical tools are essential for triaging patients and improving clinical outcomes in resource-limited emergency departments. Emergency departments play a central role in the timely assessment and management of RTI patients. The Modified Rapid Emergency Medicine Score (MREMS) has emerged as a valuable tool for predicting in-hospital mortality and other critical outcomes in emergency settings. The Modified Rapid Emergency Medicine Score (mREMS) evaluates key physiological parameters, including age, heart rate, respiratory rate, oxygen saturation, mean arterial pressure, and the Glasgow Coma Scale (GCS), to provide a rapid and standardized assessment of injury severity. Validation studies in Thailand and other regions have demonstrated mREMS's reliability in predicting in-hospital mortality and critical care needs. These studies have used performance metrics such as sensitivity, specificity, and area under the receiver operating characteristic curve (AUROC) to assess the tool's predictive accuracy. Despite these advancements, there remains a lack of validation studies in Iraq, where healthcare systems face unique challenges, including poor road safety and under-resourced emergency departments. Previous studies emphasize the importance of adapting and validating scoring systems for specific populations. In Baghdad, RTIs are a significant public health burden, but no standardized tools like mREMS have been validated in this context. This study aims to address this gap by evaluating mREMS's performance in predicting mortality, morbidity, ICU admission, and length of hospital stay requirements in RTI patients in a Baghdad hospital. The findings will contribute to improving trauma care and inform the adaptation of standardized scoring systems in Iraq.

Interventions

None listed

Sponsors

Al-Nahrain University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Written informed consent provided by the patient or a legal representative (if the patient is unconscious or unable to provide consent). * Patients presenting to the emergency department within 4 hours of the injury. * Availability of complete physiological data for MREMS calculation. * Patients whose clinical outcomes (e.g., mortality, length of hospital stay, need for intensive care) are available for follow-up and analysis.

Exclusion criteria

* Pregnant women, due to the potential risk involved in the study and unique considerations in trauma care. * Patients with pre-existing severe chronic conditions (e.g., end-stage renal disease, terminal cancer) that could severely affect outcomes. * Patients who were transferred from another hospital. * Incomplete or missing data for mREMS parameters. * Patients who leave against medical advice (LAMA) or are discharged before outcome data can be collected.

Design outcomes

Primary

MeasureTime frameDescription
In hospital mortalityIn-Hospital Phase (average of 7 days through discharge)Mortality (death) during hospitalization.
Accuracy Assessment of the modified Rapid Emergency Medicine Score (mREMS)the first 4 hours after ER admissionrange from 0 to 26. A higher mREMS score indicates a greater risk of mortality.

Secondary

MeasureTime frameDescription
Length of HospitalizationUp to discharge, an average of 7 daysThe total duration of a patient's stay in the hospital, measured from the date of admission to the date of discharge. This includes all days spent in general wards, intensive care units (ICU), and other hospital departments as part of their treatment course.
Need for ICU AdmissionUp to discharge, an average of 7 daysThe requirement for admission to the intensive care unit (ICU) is determined by the presence of severe clinical deterioration, significant complications, or the need for advanced monitoring and life-support measures.

Countries

Iraq

Contacts

STUDY_DIRECTORBashar A Abdulhassan, Assistant professor of surgery

College Of Medicine - Nahrain University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 11, 2026