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Comparison of the Acute Effects of Auricular Vagus Nerve Stimulation and Deep Breathing Exercise

Comparison of the Acute Effects of Auricular Vagus Nerve Stimulation and Deep Breathing Exercise on the Autonomic Nervous System Activity and Biomechanical Properties of the Muscle in Healthy People

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06740032
Enrollment
60
Registered
2024-12-18
Start date
2022-02-27
Completion date
2022-08-28
Last updated
2024-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vagus Nerve Stimulations

Keywords

Auricular vagus nerve stimulation, deep breathing exercises

Brief summary

The goal of this clinical trial is to investigate whether vagus stimulation and breathing exercises are more effective in healthy adults. Are vagal stimulation and breathing exercises effective on autonomic functions and the somatic system in healthy adults? Participants' results for autonomic functions and somatic system will be compared for both groups.

Interventions

OTHERTranscutaneous vagus nerve stimulation

Investigation of the effects of vagus nerve stimulation on the autonomic and somatic systems together

OTHERDeep breath exercise

Investigation of the effects of vagus nerve stimulation on the autonomic and somatic systems together

Sponsors

Bahçeşehir University
CollaboratorOTHER
Istanbul Gelisim University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* could read and write Turkish

Exclusion criteria

* being 18 years or older having no known acute or chronic disease, and no previous treatment with vagus nerve stimulation

Design outcomes

Primary

MeasureTime frameDescription
HRV results5 minutesMeasuring autonomic values for 5 minutes
Muscle Natural Oscillation Frequency5 minutesBiomechanical measurements of specific muscles
Muscle Dynamic Stiffness [N/m]5 minutesmeasured using the myoton device
Mechanical Stress Relaxation Time [ms]5 minutesmeasured using the myoton device

Secondary

MeasureTime frameDescription
Pulse rate5 minutesMeasuring with a sphygmomanometer
blood pressure5 minutesMeasuring blood pressure with a sphygmomanometer
Perceived stress scale5 minutesEvaluation of stress levels with the specified questionnaire

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026