Ovarian Hyperstimulation Syndrome Prevention

Prophylaxis Against Ovarian Hyperstimulation Syndrome in PCOS Women

Status

Recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06739759

Acronym

OHSS

Enrollment

300

Registered

2024-12-18

Start date

2024-11-17

Completion date

2025-07-30

Last updated

2024-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian Hyper Stimulation Syndrome (OHSS)

Keywords

OHSS, mild, Moderate, Severe

Brief summary

Ovarian hyperstimulation is a very hazardous complication of ICSI

Detailed description

Ovarian hyperstimulation could be mild , moderate , severe or marked

Interventions

DRUGAntagonist protocol for IVF

antagonist protocol with triggering by Decapeptyl

DRUGModified Agonist protocol for IVF with additive treatments as HCQ

giving additive drugs to agonist protocolas HCQ

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

19 Years to 42 Years

Healthy volunteers

Inclusion criteria

* Women with PCOS coming for ICSI

Exclusion criteria

* Women who donnot have PCOS

Design outcomes

Primary

Measure	Time frame	Description
prevention of OHSS	within 3 weeks	prevention of symptoms of ovarian hyperstimulation syndrome as amount of ascites in litres by US

Countries

Egypt

Contacts

Primary ContactMahmoud Alalfy, MD

mahmoudalalfy@ymail.com01002611058

Backup ContactAhmed Elgazzar, MD

elgazzara50@gmail.com01014005959

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026