Chronic Rhinosinusitis (CRS) with and Without Nasal Polyps
Conditions
Keywords
chronic rhinosinusitis, Intraoperative haemorrhage
Brief summary
The purpose of this observational study was to examine whether preoperative indicators correlate with intraoperative bleeding to facilitate control of intraoperative bleeding.
Detailed description
In this study, we analysed the effect of preoperative inflammation on intraoperative haemorrhage at the subjective and objective levels by measuring a number of indicators (including Vit D, Ca, P, and some ratios) in the blood specimens and by three scales.Blood test indicators can be obtained from routine tests.Three scales were obtained by the researcher after interviewing the patients, Symptom Score (0-15), where higher scores indicate more severe symptoms, Lund-Kennedy Score (0-6), where higher scores indicate higher levels of localised inflammation, Lund-Mackay Score (0-12 unilaterally and 24 bilaterally), where higher scores indicate higher levels of inflammation, and Lund-Mackay Score (0-12 unilaterally and 24 bilaterally), where higher scores indicate higher levels of inflammation.Lund-Mackay score (0-12 unilaterally, 24 bilaterally), where higher scores represent higher levels of inflammation.Final correlation of blood test indices and three scale scores with intraoperative.
Interventions
OTHERwithout interventios.
without interventios.
Sponsors
Nanjing First Hospital, Nanjing Medical University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
Clinical diagnosis of chronic rhinosinusitis
Exclusion criteria
Sinus cyst Upper respiratory tract infection in the last 1 week Use of antiepileptic drugs Use of aspirin Use of anticoagulant or antiplatelet drugs
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intraoperative haemorrhage | 2024/11/1-2025/7/31 | Intraoperative haemorrhage was grouped with a cut-off value of 150 ml and divided into \<150 ml (normal haemorrhage group) and ≥150 ml (high haemorrhage group). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Lund-Kennedy system | 2024/11/1-2025/7/31 | Lund-Kennedy system (0-6 scores), assessed under nasal endoscopy in terms of polyps, oedema and nasal secretions, where a higher score represents a higher level of local inflammation. |
| Symptom system | 2024/11/1-2025/7/31 | Symptom system (0-15 scores), assessed in five areas: nasal congestion, runny nose, reduced sense of smell, head and face swelling, and sleep disturbances, where higher scores represent more severe symptoms. |
| Lund-Mackay system | 2024/11/1-2025/7/31 | The Lund-Mackay system (0-12 unilaterally, 24 points in total bilaterally) analyses the inflammatory status within each sinus and the assessment of whether the sinonasal complex is obstructed in two major ways, where higher scores represent higher levels of inflammation. |
Countries
China
Outcome results
None listed