Bronchiolitis
Conditions
Keywords
bronchiolitis, bronchiolitis severity scoring, validation, utility
Brief summary
Prospective observational study of patients hospitalized with bronchiolitis. The objective of our study is to compare the accuracy of commonly used clinical scales for bronchiolitis to predict relevant outcomes.
Interventions
None listed
Sponsors
Szpital im. Św. Jadwigi Śląskiej
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
5 Weeks to 24 Months
Healthy volunteers
No
Inclusion criteria
Children eligible for the trial must fulfil all of the following criteria: 1\. Children admitted to the hospital with the clinical diagnosis of acute bronchiolitis, which is defined as an apparent viral respiratory tract infection associated with airway obstruction manifested by at least one of following symptoms: * Tachypnoea (WHO definition). * Increased respiratory effort manifested as follows: 1. Nasal flaring; 2. Grunting; 3. Use of accessory muscles; 4. Intercostal and/or subcostal chest wall retractions; 5. Apnoe. * Crackles and/or wheezing. 2. Aged 5 weeks - 24 months old.
Exclusion criteria
1\. Diagnosis or suspicion of asthma.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants requiring oxygen supplementation | From admission to hospital discharge up to 2 weeks | — |
| Duration of oxygen supplementation | From admission to hospital discharge up to 2 weeks | among those requiring oxygen |
| The time until the infant will be assessed as being 'fit for discharge' | From admission to hospital discharge up to 2 weeks | which is defined as the point at which the infant will be feeding adequately (taking \>75% of their usual intake based on parents' assessment) and will have a saturation of at least 92% for 6 h on room air, while the axillary body temperature will remain |
| Worsening of clinical status, including the following | From admission to hospital discharge up to 2 weeks | PICU admission |
| Adverse events, especially incidence of pneumonia | From admission to hospital discharge up to 2 weeks | which is defined as: * temperature increase (fever \>38 ) * deterioration of general condition * inflammatory changes in lung ultrasound or chest X-ray |
| Hospital length of stay | From admission to hospital discharge up to 2 weeks | (\> 3 days) |
Countries
Poland
Contacts
Primary ContactHenryk Szymański MD PhD
Outcome results
None listed