Recurrent Thyroid Cancer
Conditions
Brief summary
To evaluate the long-term outcomes of ultrasound-guided thermal ablation for recurrent thyroid cancer
Detailed description
To evaluate and predict the long-term outcomes of ultrasound-guided thermal ablation for recurrent thyroid cancer by a multicenter study
Interventions
PROCEDUREultrasound-guided thermal ablation
microwave ablation, radiofrequency ablation, laser ablation
Sponsors
Chinese PLA General Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. patient received thyroidectomy for thyroid cancer 2. recurrent lesions were pathologically proven to be malignant by core-needle biopsy or fine needle aspiration 3. no evidence of distant metastases. 4. follow-up period ≥12 months
Exclusion criteria
1. coagulation disorder, serious heart, respiratory, liver, or renal failure 2. dysfunction of the vocal cord on the opposite side
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| rate of disease progression | through study completion, an average of 6 months | cervical lymph node metastases and persistent tumors confirmed by pathology, Distant metastasis detected by CT, positron emission tomography, or bone scan if there were suspicious symptoms. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| rate of delayed surgery | through study completion, an average of 1 year | patients underwent surgery after ablation because of anxiety |
| rate of tumor disappearance | through study completion, an average of 6 months | complete disappearance of ablated tumor on ultrasound and contrast-enhanced ultrasound |
| Tg level | through study completion, an average of 6 months | serum thyroglobulin level |
| rate of complications | 1 week | complication of ablation |
| rate of volume reduction | through study completion, an average of 6 months | volume reduction of tumor after ablation on ultrasound and contrast-enhanced ultrasound |
Countries
China
Contacts
Primary ContactLin Yan
Outcome results
None listed