Strenght Training in Osteoporosis Prevention

Effective Prevention of Osteoporosis Through Rehabilitation and Training

Status

Active, not recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06733064

Acronym

SPORT

Enrollment

120

Registered

2024-12-13

Start date

2024-09-02

Completion date

2026-01-30

Last updated

2024-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteopenia or Osteoporosis

Keywords

strenght training, vitamin d3, osteoporosis, osteopenia

Brief summary

The study involves 120 women over the age of 50. All participants in the study take part in high-intensity strength training for 10 months. In addition, half of the participants receive vitamin D3 at a dose of 4,000 IU/day. The investigators hypothesize that training combined with vitamin D3 supplementation will be more effective in preventing osteoporosis than training alone.

Interventions

DIETARY_SUPPLEMENTSupplementation of vitamin D3

Supplementation of vitamin d3 at a dose of 4000 iu / day

DIETARY_SUPPLEMENTPlacebo

Vegetable oil as a placebo

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Age

50 Years to No maximum

Healthy volunteers

Inclusion criteria

* age over 50 * female

Exclusion criteria

* ongoing cancer, * unstabilized cardiovascular disease, * cognitive disorders, * radiological treatment in the last 12 months, * other contraindications to undertaking high-intensity strength training, * diseases affecting the skeleton such as: Paget's disease, type I diabetes mellitus, * taking medications affecting skeletal conditions including: long-term therapy with corticosteroids, thiazides, antiretroviral drugs, * contraindications to taking vitamin D including: hypercalcemia, nephrolithiasis, sarcoidosis, lack of cholecalciferol hydroxylase activity in the liver and kidneys.

Design outcomes

Primary

Measure	Time frame	Description
Bone Mineral Density	Measured at 3 time points: before the experiment, after 10 months of training, and at 6 months after the end of training and supplementation.	Test to determine bone mineral density by densitometry.

Secondary

Measure	Time frame	Description
Vitamin D metabolites level	Measured at 4 time points: before the experiment, after 5 and 10 months of training, and at 6 months after the end of training and supplementation.	Measurement evaluating the levels of selected vitamin D3 metabolites by LC-MS.

Countries

Poland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026