Hidradenitis Suppurativa (Acne Inversa)
Conditions
Keywords
punch biopsy tool, drainage, abscess, I&D
Brief summary
This randomized-control trial is designed to determine the recurrence rate of HS abscesses following drainage via two methods: I&D with a linear incision and PD with an 8mm punch biopsy. In this context, recurrence is a newly described HS abscess adjacent to or within the previously operated area, for which a second intervention is deemed necessary. We hypothesize that PD may yield a more favorable recurrence rate. In addition to comparing recurrence rates, this randomized-control trial will also evaluate postprocedural pain, the occurrence and type of complications, and patients' quality of life associated with both procedures. These additional factors are crucial in assessing the overall effectiveness and patient satisfaction associated with each method, further informing the potential establishment of PD as the new gold standard for draining small, painful, acute HS abscesses.
Interventions
PROCEDUREPunch Debridement
A punch biopsy tool is positioned over the inflamed follicular unit, and a small circle of skin (4 to 8 mm in diameter) is excised. A firm twisting motion is necessary to ensure adequately deep excision.
PROCEDUREIncision and Drainage
Incision and Drainage is a minimally invasive surgical procedure often employed for the treatment of intensely painful, tense, and fluctuant abscesses that are too deep to drain spontaneously. After administration of a broad circumferential local anesthetic, a small linear incision is made using a standard scalpel blade. Digital pressure is applied to expel the fluid collection. Saline rinses can be used to flush out the remaining contents. This method offers instant pain relief, commonly performed in acute settings by dermatologists, emergency department physicians and general practitioners
Sponsors
Erasmus Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
RCT with two intervention groups, one of which is gold standard intervention
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosed with HS * Has an abscess requiring drainage with a maximum diameter of 5 centimeters. * Age 16 years or older * Willing and able to provide informed consent
Exclusion criteria
* Has other conditions that could interfere with the study, as estimated by physician * Unable to comply with follow-up visits * Allergic to lidocaine and/or adrenaline.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Recurrence | 1 month | Recurrence rate in percentage of abscesses recurring after drainage |
Countries
Netherlands
Contacts
Primary ContactHessel H van der Zee, MD, PhD
Outcome results
None listed