Association Between Blood Pressure and Risk of PSCI

Association Between Blood Pressure and the Risk of Post-stroke Cognitive Impairment: a Retrospective Cohort Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06730711

Enrollment

600

Registered

2024-12-12

Start date

2024-09-01

Completion date

2024-12-30

Last updated

2024-12-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Pressure, Cognitive Decline, Stroke

Keywords

stroke, cognitive impairment, blood pressure

Brief summary

This retrospective cohort study was designed to explore the relationship between blood pressure and cognitive impairment after stroke

Detailed description

Patients who have been followed up for more than 3 months after stroke will be included in the study. Basic data of patients and factors that may be related to cognitive impairment will be collected, and the relationship between blood pressure and cognitive impairment after stroke will be explored by univariate regression analysis and multivariate regression analysis. Univariate logistic regression model and multivariate logistic regression model were used to explore the relationship between blood pressure level and the risk of cognitive impairment after stroke, and the effect of blood pressure level and cognitive impairment sub-line in different patients was evaluated by subgroup analysis.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

1. Patient diagnosed with stroke by CT or MRI, 2. Patients completed the MMSE scale at least once during hospitalization 3. The follow-up time was more than three months after the stroke occurred;

Exclusion criteria

1. Patients with incomplete data, follow-up time less than three months after the stroke occurred less than 3 months, 2. Patients with pre-existing cognitive impairment before stroke according to their medical records, 3. patients failed to complete MMSE assessment because of aphasia or any other reasons, 4. Patients combined with malignant tumors, patients combined with psychiatric disorders.

Design outcomes

Primary

Measure	Time frame	Description
Mental State Examination Scale (MMSE)	Mini-Mental State Examination (MMSE) assessment will be completeed at 3 monthes after stroke	Global cognitive function assessment. Easy to use and one of the most used scales to screen person with cognitive impairment in the world. The minimum and maximum values range from 0 to 30. Higher score means better cognition level.

Countries

China

Contacts

Primary ContactDingqun Bai

baidingqun@hospital.cqmu.edu.cn13808380876

Backup ContactDefei Chen

2283273437@qq.com+8615188017034

Outcome results