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Thumb Muscle Thickness and Strength in CMC Osteoarthritis

Ultrasonographic Measurement of Thumb Muscle Thickness and Evaluation of Pinch and Grip Strength in First Carpometacarpal Joint Osteoarthritis: A Comparison of Early and Advanced Stages

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06730698
Enrollment
34
Registered
2024-12-12
Start date
2024-12-10
Completion date
2025-01-20
Last updated
2025-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Brief summary

A total of 34 patients aged between 50-80 years, diagnosed with first carpometacarpal joint osteoarthritis based on hand radiographs taken within the last 3 months, will be included in the study from the Physical Therapy and Rehabilitation outpatient clinic. Sociodemographic data such as age, gender, height, weight, and BMI will be recorded. Based on their current radiographs, patients will be classified into two groups according to the Eaton-Littler classification: Stage 1-2 (early stage) and Stage 3-4 (advanced stage). Pain levels will be assessed using the Visual Analog Scale (VAS). Hand grip strength will be evaluated with a Jamar hand dynamometer, and pinch grip strength will be assessed with a Jamar pinch meter. The thicknesses of the abductor pollicis brevis, first dorsal interosseous, and opponens pollicis muscles will be measured using ultrasound. All assessments will be performed separately for the dominant and non-dominant hands.

Interventions

OTHERNo intervention

No intervention

Sponsors

Beylikduzu State Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
50 Years to 80 Years

Inclusion criteria

* Patients aged 50-80 years. * Diagnosed with first carpometacarpal joint osteoarthritis. * Presence of a hand radiograph taken within the last 3 months. * Volunteered to participate in the study.

Exclusion criteria

* Refusal to participate in the study. * Use of medications that may suppress osteoarthritis flares. * Presence of rheumatologic diseases causing peripheral joint involvement. * History of fractures or surgeries involving the first carpometacarpal joint. * Presence of psychiatric disorders. * Presence of cognitive impairments that could hinder understanding or performance of study-related tasks.

Design outcomes

Primary

MeasureTime frameDescription
Thumb Muscle Thickness (Ultrasound)0 dayMeasurement of the thickness of three thumb muscles-abductor pollicis brevis, first dorsal interosseous, and opponens pollicis-using ultrasonography. These measurements will help determine muscle atrophy or hypertrophy related to disease severity and stage

Secondary

MeasureTime frameDescription
Grip Strength0 dayAssessed using a Jamar hand dynamometer. This measure evaluates overall hand strength, which is often impaired in advanced stages of carpometacarpal joint osteoarthritis.
Pinch Strength0 dayAssessed using a Jamar pinch meter. This measure evaluates the strength of the thumb-index finger pinch, a critical function for fine motor activities. It is particularly relevant to functional limitations seen in osteoarthritis.
Pain Level (VAS)0 dayPain intensity will be measured using the Visual Analog Scale (VAS). Patients will mark their perceived pain level on a 10 cm scale, providing a quantitative measure of pain severity in both early and advanced stages.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026