The Value of 68Ga-FAPI PET/CT in Preoperative Evaluation of Thyroid Cancer with Lymph Node Metastases

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06730529

Enrollment

Registered

2024-12-12

Start date

2024-11-29

Completion date

2029-12-31

Last updated

2024-12-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Cancer

Keywords

Thyroid Cancer, 68Ga-FAPI, PET/CT

Brief summary

This study aims to investigate the value of 68Ga-FAPI in the preoperative evaluation of thyroid cancer of different pathologic types.

Detailed description

The investigators will number all participants, create a medical record file, and record their basic information (gender, age) as well as contact information and medical history information. All participants will undergo a 68Ga-FAPI PET/CT before surgery. The imaging response measurements will be compared with the histopathological results as gold standard.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

16 Years to 80 Years

Healthy volunteers

Inclusion criteria

1. Pathological and clinical diagnosis of thyroid cancer with lymph node metastases. 2. Signed and dated informed consent form. 3. Commitment to comply with research procedures and co-operation in the implementation of the full research process. 4. Aged 16-80 years old.

Exclusion criteria

1. Patients with serious illnesses that researchers consider unsuitable for participation in this clinical study. Such as severe heart and lung failure, severe bone marrow suppression, severe liver and kidney dysfunction, etc. 2. Intestinal perforation, complete intestinal obstruction. 3. Pregnant women and women who may be pregnant, women who are breastfeeding. 4. Non-compliant person.

Design outcomes

Primary

Measure	Time frame	Description
Clinical staging of thyroid cancer with lymph node metastasis	Within 1 week after enrollment	The value of 68Ga-FAPI PET/CT in the evaluation of thyroid cancer with lymph node metastases in clinical staging

Secondary

Measure	Time frame	Description
Standardized uptake value(SUV)	Within 1 week after enrollment	SUV of 68Ga-FAPI uptake on PET/CT images for tumor lesions
Disease free survival	3 years	Disease free survival

Countries

China

Contacts

Primary ContactJiajia Hu

jiajiahu@shsmu.edu.cn13524945287

Outcome results