Myocardial Injury, Myocardial Injury After Non-Cardiac Surgery
Conditions
Brief summary
The aim of this study is to gain insight into the etiology of myocardial injury after non cardiac surgery. Furthermore, suspected etiologies were explored and hierarchically classified into most likely cause how this determines prognosis and what factors are associated with improved outcome.
Detailed description
As above
Interventions
OTHERHigh sensitive Troponin T
The baseline population will consist of all patients who underwent a form of non-cardiac surgery. Baseline variables, medication use, type of surgery and perioperative hemodynamic and laboratory variables will be extracted from the hospital information system. One year mortality is registered, as well as major vascular events. This is in line with previous publications from our group. The adjudication strategy used for patients with myocardial injury. For the adjudication process minimal two senior anesthesiologists will be invited. Two members with at least one senior anesthesiologist will receive a sample of patients to adjudicate. Together the entire panel will adjudicate all patients. The goal to investigate the differences between the raters.
Sponsors
Erasmus Medical Center
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age \> 18 year of age * Undergoing non-cardiac surgery in the Erasmus MC, with (high-sensitive) Troponin T \> 50 ng/L measured in any of the first three days after surgery.
Exclusion criteria
* Re-operations within the study period. * Daycare surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Main etiologies elevated troponin T | from enrollment | The primary endpoint is a description of the main etiologies found within patients with an elevated troponin T after non cardiac surgery. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Differences in adjudication | from enrollment | Differences in the adjudication process between different doctors will be assessed according to intraclass coeficients and Fleisch Kappa |
Countries
Netherlands
Outcome results
None listed