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Assessment of Pre Hospital Rescue Intervention for Seizure in Pediatric Patients

Assessment of Pre Hospital Rescue Intervention for Seizure in Pediatric Patients

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06723431
Enrollment
50
Registered
2024-12-09
Start date
2025-01-31
Completion date
2025-11-30
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Seizure

Keywords

seizure in pediatric patients

Brief summary

1. Evaluation of pre hospital rescue intervention of seizure management. 2. To investigate the type of rescue medication, Efficacy, route of administration, Side effects of this drug, frequency and Indication of its use.

Detailed description

An epileptic seizure is a transient occurrence with signs or symptoms due to abnormal excessive and synchronous neuronal activity in the brain. There are many different types of seizures: Current classification designates two large categories - partial or generalized. In a partial seizure, one area of the cortex is thought to be activated initially and may show simple symptoms such as a motor or sensory phenomena. Partial seizures may rapidly secondarily generalize and spread to involve all cortical areas. Generalized seizures result from diffuse cortical activation at seizure onset . Seizure cluster provides an opportunity to administer prompt treatment. Delays in the treatment of seizure emergencies are often associated with negative patient outcomes. Seizure clusters become less responsive to treatment when they continue unabated over time . In addition to using anti epileptic medications, the treatment of seizures aims at correcting any identifiable causative process. Care is needed to prevent any secondary brain injury, which may include advanced respiratory and cardiovascular support. Monitoring is necessary to detect hypotension and hypoxia and steps taken to correct those conditions when recognized. Common complications may include traumatic injuries such as tongue lacerations or scalp lacerations . Convulsive status epileptic leads to brain damage on the cellular level and may itself be epileptogenic. Transformed or subtle generalized convulsive status epileptic or non convulsive seizures detected by EEG monitoring in critically ill patients may also contribute to brain laceration .

Interventions

None listed

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
2 Years to 18 Years
Healthy volunteers
No

Inclusion criteria

* Patient with recurrent attack of seizure and with prolonged seizure with prescribed treatment at home. * Patients aged from 2 years to 18 years

Exclusion criteria

* First attack of seizure * condition mimic epilepsy

Design outcomes

Primary

MeasureTime frameDescription
Aim of the studyBaseline1. Evaluation of prehospital rescue intervention of seizure management. 2. To investigate the type of rescue medication, 1. it's Efficacy. 2. it's route of administration. 3. Side effects of this drug. 4. frequency . 5. Indication of it's use.

Secondary

MeasureTime frameDescription
Seizure triggersBaselineSeizures can be triggered by things in the environment. Seizure triggers don't cause epilepsy, but they may trigger seizures in people who have epilepsy. Most people with epilepsy don't have reliable triggers that always cause a seizure. However, they often can identify factors that make it easier to have a seizure. Possible :seizure triggers include * Illness * Skipping doses of antiseizure medicines or taking more than prescribed. * Dehydration * Lack of sleep * Flashing lights * Stress * Hormone changes during the menstrual cycle• Illicit drug use * Skipped meals

Contacts

Primary ContactSamah Gamal Hussien, doctor
samahelewa085@gmail.com+201025389433
Backup ContactFatma abdelfatah ali
0 1006347038

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026