Shivering, Spinal Anesthesia
Conditions
Keywords
shivering, Spinal anesthesia, Ketamine, Tramadol and Metclopromide
Brief summary
\*Ketamine:\* Ketamine is a medication that can help reduce shivering by blocking certain nerve signals in the brain. It's like a nerve blocker that helps calm down the body's shivering response. \- \*Tramadol:\* Tramadol is a pain medication that can also help reduce shivering. It works by affecting the brain's temperature regulation centers, which helps to reduce the shivering response.
Detailed description
Post-spinal shivering is when a patient starts shaking or shivering after receiving spinal anesthesia. This can be uncomfortable and even scary for the patient. Using ketamine and tramadol to reduce post-spinal shivering can have several benefits, including: * Reduced discomfort and anxiety for the patient * Improved patient satisfaction * Reduced need for additional medications or interventions * Faster recovery times
Interventions
DRUGKetamine only
Inj: Ketamine given to group K following spinal anesthesia
DRUGTramadol
Inj Tramadol given to group T following spinal anesthesia
Sponsors
Liaquat National Hospital & Medical College
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Pateint for elective cesarean section * Age 18 to 40 years * ASA 1 and 2
Exclusion criteria
* ASA 2 and 3 * Cesarean section requiring general anesthesia * Hypersensitivity to Ketamine, Tramadol and Opiods * History of cardiovascular disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Shivering | 20 minutes to 12 hours | Scale validated by crossley and mahajan Grade 0: No shivering Grade 1: Piloerection, peripheral vasoconstriction, peripheral cyanosis, or mild fasciculation of the face or neck, but no visible muscle activity Grade 2: Visible muscle activity in one muscle group Grade 3: Visible muscle activity in more than one muscle group Grade 4: Gross muscle activity involving the entire body |
Countries
Pakistan
Contacts
Primary ContactNazish Dr Nazish Kanwal
Backup ContactShazor khan Khattak
Outcome results
None listed