Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

Black and African Americans Connections to Parkinson's Disease (BLAAC PD) A Project of the Global Parkinson's Genetics Program (GP2)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06719583

Acronym

BLAAC PD

Enrollment

2000

Registered

2024-12-06

Start date

2020-11-16

Completion date

2027-12-31

Last updated

2026-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson Disease

Keywords

genetics, underrepresented

Brief summary

BLAAC PD is a research study to understand what Parkinson's disease looks like for Black and African American communities. BLAAC PD is happening at research centers around the United States. The study is part of the Global Parkinson's Genetics Program (GP2). GP2 is a research project working to transform understanding of the genetics of Parkinson's disease and make that knowledge globally relevant.

Detailed description

Research studies have found connections between genes and Parkinson's disease (PD). But those results have mostly come from studies with non-Black or African American volunteers. BLAAC PD aims to learn more about gene changes that may cause Parkinson's in Black and African American people. Study volunteers at sites across the United States will attend one visit and will give either a blood or saliva sample, complete a smell test, and may be asked to complete a physical exam. This new data could lead to future Parkinson's tests and treatments for Black and African American people and it may help better understand disease in other groups, too. This pioneering initiative will fill a gap of knowledge about PD in Black and African American people.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

for Control Participants: * Ability to provide informed consent * Age 50 years or older * Self-identify as Black or African American

Exclusion criteria

for Control Participants: * Diagnosis of Parkinson's Disease and/or neurological condition * Familial history of PD and/or neurodegenerative or psychiatric conditions * Unknown family history of PD and/or neurodegenerative or psychiatric conditions * Any conditions that, in the investigator's opinion, preclude the individual's ability to carry out study activities * If submitting a saliva sample, nothing by mouth (food, drink, gum, tobacco, or smoking) for 30 minutes prior to sample collection Inclusion Criteria for Participants with a Diagnosis of PD: * Ability to provide informed consent * Age 18 years or older * Self-identify as Black or African American * Meet the Movement Disorder Society's clinical diagnostic criteria for Parkinson's disease

Design outcomes

Primary

Measure	Time frame	Description
Explore novel risk factors and characterization	5 years	To explore novel risk factors and characterization of known genetic risk factors contributing to Parkinson's disease risk in the Black and African American population.

Countries

United States

Contacts

CONTACTNaomi Louie, MPH RDN

nlouie@michaeljfox.org212-509-0995

PRINCIPAL_INVESTIGATORLana Chahine, MD, PhD

University of Pittsburgh

Outcome results