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Evaluation of Gas Humidification Practices in Patients Under Invasive Mechanical Ventilation

Evaluation of Gas Humidification Practices in Patients Under Invasive Mechanical Ventilation: Benefit of the F & P950 Heated Humidifier: Comparison With the MR 850 on Clinical Events of Under-humidification

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06719258
Acronym
FP950
Enrollment
40
Registered
2024-12-05
Start date
2024-09-20
Completion date
2026-07-31
Last updated
2025-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Humidifier Lung, Mechanical Fragility, Respiratory Complication

Brief summary

When mechanical ventilation is initiated, a humidification method should be chosen. There is two methods: heat and humidity exchanger filters or heated humidity. The second method is recognized to be more efficient, but many external factors can influence its performance. Insufficient humidity results in observable problems, such as difficult management of respiratory secretions. The study compare two heated humidifiers already used in ICU. Data will be collected retrospectively from June 1, 2021.

Interventions

DEVICEMR850

This humidifier will be used straight away for patients whose intubation is expected to last longer than 24 hours.

DEVICEFP950

This humidifier will be used straight away for patients whose intubation is expected to last longer than 24 hours.

Sponsors

Laval University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* ≥ 18 years old * Admitted to intensive care * Under invasive mechanical ventilation with the usual indications for the use of a heated humidifier (prolonged invasive mechanical ventilation and / or protective ventilation requiring high respiratory rates.

Exclusion criteria

* Mechanical venitilation immediately after surgery (\<24h) * Imminent extubation or planned intubation of very short duration (\<24h) * Enrolled in the SAVE-ICU study in the group receiving volatile agents with the AnaConDa system.

Design outcomes

Primary

MeasureTime frameDescription
Endotracheal tube occlusion requiring emergency tube changeAt the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)Under-humidification episodes are defined as follows: \- Occurence of endotracheal tube occlusion requiring emergency tube change
BronchoscopyAt the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)Under-humidification episodes are defined as follows: \- Occurence of performing a bronchoscopy for a suspected sub-occlusion (thick or sticky secretions), and the total number of bronchoscopies performed per patient
Tracheal saline instillationsAt the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)Under-humidification episodes are defined as follows: \- Occurence of tracheal saline instillations due to sticky secretions or suspected endotracheal tube sub-occlusion
Thick secretionsAt the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)Under-humidification episodes are defined as follows: \- Occurence of tracheal secretions describe at thick secretions (rated at 5 on the secretions scale used at the hospital) or sticky secretions if specified
Change humidifier settingsAt the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)Under-humidification episodes are defined as follows: \- The number of operations required to change humidifier settings if the plate temperature is below 62 degrees Celcius (with the MR850).

Secondary

MeasureTime frameDescription
Other elements that may be influenced by the quality of the humidification used during mechanical ventilationAt the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)These data will be collected: * mechanical ventilation time * length of stay in intensive care * ventilation pressures * use of bronchodilator aerosols. * Ambien room air temperature

Countries

Canada

Contacts

Primary ContactFrançois Lellouche
francois.lellouche@criucpq.ulaval.ca418-656-8711
Backup ContactPierre-Alexandre Bouchard
pierre-alexandre.bouchard@criucpq.ulaval.ca418-656-8711

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026