Non Alcoholic Fatty Liver, Phenylketonurias
Conditions
Brief summary
phenylketonuria (commonly known as PKU) is an inherited disorder that increases the levels of a substance called phenylalanine in the blood. PKU is usually associated with many metabolic complication including non-alcoholic fatty liver
Detailed description
this study will include PKU children sufferers 9n=40) with non-alcoholic fatty liver to be randomly assigned to group I (n=20) that will perform walking program (online supervised free walking that will be applied daily for eight weeks) or group II (N=20) that will act as waitlisted children
Interventions
BEHAVIORALwalking free online supervised program
this Group I will include PKU children sufferers (n=20) with non-alcoholic fatty liver that will perform walking program (online supervised free walking that will be applied daily for eight weeks)
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
9 Years to 12 Years
Healthy volunteers
No
Inclusion criteria
* PKU children * obese children * fatty liver children (non-alcoholic fatty liver)
Exclusion criteria
* cardiac children * diabetic children * neurogenic disorders * respiratory and renal problems
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| alanine transamianse | it will be assessed after eight weeks | it is a serum liver enzyme |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| aspartate tranaminase | it will be assessed after eight weeks | it is a serum liver enzyme |
| Gamma-glutamyl Transferase | it will be assessed after eight weeks | it is a serum liver enzyme |
| alkaline phosphatase | it will be assessed after eight weeks | it is a serum liver enzyme |
| triglycerides | it will be assessed after eight weeks | it will be measured in the serum |
| body mass index | it will be assessed after eight weeks | it will be measured after emptying bladder |
Countries
Egypt
Contacts
Primary ContactAli Isamil, Lecturer
Backup Contactshimaaa bondok, PHD
Outcome results
None listed