Assessment of Hematologic Indices in Juvenile Lupus Erythematosus Patients:Correlation With Disease Activity and Chronic Organ Damage in These Patients

Assessment of Hematologic Indices in Juvenile Lupus Erythematosus Patients : Correlation With Disease Activity and Chronic Organ Damage in These Patients

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06718283

Enrollment

Registered

2024-12-05

Start date

2024-11-30

Completion date

2026-02-02

Last updated

2024-12-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Juvenile Systemic Lupus Erythematosus

Brief summary

The study aim to evaluate the relationship between some important hematologic indices in juvenile lupus erythematosus patients and if these indices may be use as markers of disease acitivity in these patients or not ,also evaluate the relationship with these markers and chronic organ damage index

Detailed description

We calculate important hematologic indices in children diagnosed as SLE as systemic inflamatory index ,systemic inflamatory response index and aggregate index of systemic inflamation in these patients ,and correlate these indices with SLE disease activity index and chronic damage index in these patients.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 18 Years

Inclusion criteria

* patients who fillful 2012 SLICC criteria or 2019 ACR/EULAR criteria of systemic lupus erythematosus * Age of patients at disease onset before 18 years

Exclusion criteria

* Adult onset disease ( age at disease onset after 18 years * Any other chronic inflamatory disorders or other autoimmune diseases

Design outcomes

Primary

Measure	Time frame	Description
Correlation between hematologic indices in juvenile lupus erythematosus patients and disease activity in these patients	3-6 months	SLEDAI score in juvenile lupus erythematosus patients
Calculation of hematological indices in juvenile lupus erythematosus patients	3_ 6 months	Calculation of systemic inflamatory index,systemic information response index and aggregate index of systemic inflamation ,and correlate these indices to SLE disease activity index

Secondary

Measure	Time frame	Description
Calculation of chronic damage index in juvenile lupus erythematosus patients	3_6 months	SLICC/ACR score in juvenile lupus erythematosus patients
Relationship between hematologic index and chronic organ damage index in juvenile lupus erythematosus patients	3-6 months	SLICC/ACR score

Countries

Egypt

Contacts

Primary ContactAlshimaa H Khalaf

elshimaa011054@med.sohag.edu.eg01067790054

Backup ContactEsam M Abualfadl

01123977966

Outcome results