Effect of Lidocaine in Reducing Opioids Requirement in Day Care Surgery

Efficacy of Lidocaine in Decreasing Perioperative Analgesic Opioids Requirement After Ambulatory Surgery

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06717672

Enrollment

Registered

2024-12-05

Start date

2023-11-05

Completion date

2024-05-10

Last updated

2024-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Post-operative Pain, Post-operative Pain Control

Keywords

Lidocaine, Opiods, Peri-operative pain, Decrease Opioid requirement, Ambulatory surgeries

Brief summary

1. \*Reduced opioid consumption 2. \*Decreased pain scores 3. \*Fewer opioid-related side effects 4. \*Improved patient satisfaction

Detailed description

Studies have shown that lidocaine can reduce opioid consumption by 20-50% in the perioperative period. Studies have shown that lidocaine can reduce opioid consumption by 20-50% in the perioperative period. By reducing opioid consumption, lidocaine can also decrease the incidence of opioid-related side effects, such as nausea, vomiting, and respiratory depression. Lidocaine's analgesic effects can improve patient satisfaction and reduce anxiety related to pain

Interventions

DRUGNormal Saline

Normal saline used is an iv fluid given for fluid replacement

DRUGLidocaine 2% without vessel constrictor

1. \_Lidocaine 2% provides rapid and effective local anesthesia for minor surgical procedures, such as biopsies, excisions, and suturing. 2. \_Pain relief\_: Lidocaine 2% has been shown to provide significant pain relief in patients with acute pain, such as post-operative pain, trauma, and burns. 3. \_Reducing pain intensity\_: Lidocaine 2% has been shown to reduce pain intensity by 30-50% in various clinical studies.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* ASA 1 and 2 * patient age between 18 and 65 years * Patient undergoing ambulatory surgeries

Exclusion criteria

* Pregnant women * Allergic to Lidocaine Patient who had fever and treated with antibiotic and steroid in last month

Design outcomes

Primary

Measure	Time frame	Description
Peri-operative pain	at 2 hours, 4 hours, 6 hours	Visual Analog pain scale to rate pain scale comprises 0 to 10 score 0 minimum to 10 Maximum

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026