Socket Preservation After Surgical Extraction of Impacted Lower Third Molar

Socket Preservation Using Autogenous Particulate Dentin in Combination With Liquid Platelet-rich Fibrin Versus Bone Allografts and Collagen Cones After Surgical Extraction of Impacted Lower Third Molar

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06716736

Enrollment

Registered

2024-12-04

Start date

2022-12-01

Completion date

2024-04-01

Last updated

2024-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Socket Preservation

Keywords

socket preservation, dentine graft

Brief summary

The aim of this study will be to evaluate socket preservation using autogenous particulate dentin in combination with liquid platelet-rich fibrin versus bone allografts and collagen cone after surgical extraction of the horizontally impacted lower third molar

Detailed description

The aim of this study will be to evaluate socket preservation using autogenous particulate dentin in combination with liquid platelet-rich fibrin (sticky tooth) versus bone allografts and collagen cone after surgical extraction of the horizontally impacted lower third molar

Interventions

BIOLOGICALsocket preservation using dentine graft mixed with i-PRF

surgical extraction of horizontally impacted third molar , placement of dentin graft mixed with i-PRF inside the socket , suturing

BIOLOGICALsocket preservation using bone allograft

surgical extraction of horizontally impacted third molar , placement of bone allograft inside the socket , suturing

BIOLOGICALsocket preservation using collagen cone

surgical extraction of horizontally impacted third molar , placement of collagen cone inside the socket , suturing

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 35 Years

Healthy volunteers

Inclusion criteria

1. Fresh extracted socket of horizontally impacted mandibular third molar 2. Co-operative patients willing to complete the follow-up periods. 3. Patients age from 18-35 years. 4. Good oral hygiene.

Exclusion criteria

1. Any pathological condition at the site of surgery. 2. Patients with systemic diseases that contra-indicate the surgical procedure such as uncontrolled diabetes mellitus, bleeding disorders, serious osseous disorders and mental disorders. 3. Smokers . 4. Pregnancy. \-

Design outcomes

Primary

Measure	Time frame	Description
bone resorption distal to second molar	3 months after extraction	by measuring bone level immediate and 3 months after extraction on CBCT

Secondary

Measure	Time frame	Description
bone density	3 months after extraction	using CBCT 3 month after extraction
edema	4 days after extraction	by measuring distance between predetermined anatomical landmarks: * Mandibular angle and canthus of the eye. * Mandibular angle and corner of the mouth. * Mandibular angle and tragus. * Mandibular angle and pogonion.
pain after surgical extraction	4 days after extraction	using numerical rating scale

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026