Microecological Therapy, Probiotic Intervention
Conditions
Keywords
probiotics, safty, microecological therapy
Brief summary
We have discovered a type of probiotic that can target activating intestinal NOD2, which is related to a series of human health issues.
Detailed description
This trial requires the subjects to take probiotics for a certain period of time, and we will collect blood, stool and questionnaires for subsequent testing, efficacy evaluation and safety evaluation.
Interventions
OTHEROral administration
Take it directly
Sponsors
Zhujiang Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* Tend to participate the trial * Willing to provide written informed consent
Exclusion criteria
* Recent use of probiotics, antibiotics, laxatives, or gastrointestinal ulcer medications within the past month. * Gastrointestinal symptoms (e.g., constipation, abdominal pain, diarrhea, melena, hematochezia) in the past month. * Other conditions considered by researchers for exclusion
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| safty | up to 2 weeks | Adverse reaction by questionnaire survey |
| NOD2 activation level | up to 2 weeks | the level of NOD2 activation by fecal in vitro experiments |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Intestinal barrier | up to 2 weeks | Intestinal Barrier markers |
Countries
China
Outcome results
None listed