The Value of Near-infrared Spectroscopy and Blood Pressure Measurements in Estimating Future Fall Risk in Older Adults

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06714565

Acronym

NIRS-Fall

Enrollment

141

Registered

2024-12-03

Start date

2024-12-04

Completion date

2026-12-05

Last updated

2024-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Falls, Older Adults (65 Years and Older), Orthostatic Hypotension

Keywords

falls, orthostatic hypotension, blood pressure, NIRS, Older adults

Brief summary

The investigators aim to study which measurements/definitions from continuous blood pressures measurements (using a Finometer) and from cerebral oxygenation measurements (using near-infrared spectroscopy (NIRS)) are associated with future fall incidents in older adults at risk of falls.

Detailed description

Patients aged 65 years and over with a fall in the last 12 months are eligible for inclusion. After being informed about the study, all participants giving written informed consent will perform the active stand procedure (5min lying, 5 min standing). The hemodynamic measurements that will be performed during this procedure simultaneously consist of: 1. Volume-clamp photoplethysmography on the finger in the digital artery (Finapres medical systems, Enschede, The Netherlands) for continuous blood pressure measurements. 2. PortaLite MKII (Artinis medical systems, Elst, The Netherlands) for continuous cerebral oximetry (NIRS). After completing the measurements, participants will receive a falls calendar and will be instructed to record falls, fall-related injuries, and fall-related healthcare use on a weekly basis for 12 months.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* 65 years or older * History of a fall (in the past year) * Ability to perform supine-to-stand manoeuvres. * Ability to sign informed consent. * a Mini-Mental State Examination (MMSE) score of 21 points or higher or a Montreal Cognitive Assessment (MOCA) - Dutch score of 16 points or higher. * Sufficient command of the Dutch language

Exclusion criteria

* Physically not able to perform sit-to-stand and supine-to-stand manoeuvres. * Estimated life expectancy of less than one year.

Design outcomes

Primary

Measure	Time frame	Description
Falls during follow-up	From enrollment to 12 months follow-up	Falls data prospectively collected using fall calenders.

Countries

Netherlands

Contacts

Primary ContactAnouschka C. Pronk, MD, PhD student

a.c.pronk@amsterdamumc.nl+31205669111

Outcome results