Anesthesia, Breast Cancer, Mastectomy, Pain, Postoperative
Conditions
Brief summary
The Serrato Posterosuperior Block (SPSIP) is a recently discovered technique that provides analgesia to the hemithorax, shoulders, neck and back. At an anatomical level, it has been seen that this technique allows the diffusion of local anesthetic starting from C7 proceeding dorsally up to T10 by sectioning the trapezius, latissimus dorsi, rhomboid and erector spinae muscles. The serratus anterior block (SAPB) is a technique that allows local anesthetic to be injected between the serratus anterior muscle and the intercostal muscles (deep plane) or between the latissimus dorsi muscle and the serratus anterior muscle (superficial plane), also providing analgesia at of the chest wall. This study aims to compare the analgesic efficacy of SPSIPB and SAPB in patients undergoing radical mastectomy for breast cancer
Interventions
PROCEDURESerratus Posterior Superior Plane Intercostal Plane block
Under ultrasound guidance; local anesthetic will be injected in the plane between the posterior aspect of the serratus posterior superior plane and the ribs
PROCEDURESerratus Anterior Plane block
Under ultrasound guidance; local anesthetic will be injected in the plane between the posterior aspect of the serratus anterior and the external intercostal muscles and ribs
Sponsors
Azienda Ulss 6 Euganea
Ospedale di Camposampiero
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult Patient ( \> 18 years) * Informed consent * American Society of Anaesthesiologis Phisical Status I to III * Patients undergoing for mastectomy with sentinel lynphnode byopsy/axillary clearence
Exclusion criteria
* Pregnant women * Allergy to any drug present in the protocol
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain at 0 hours after surgery | 0 hours after surgery | The primary objective of the study is to evaluate whether there is a difference between SAP block and SPSIP block at 0 hours after surgery at rest measure with visual analogic scale (0-10) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain at 12 hours after surgery | 12 hours after surgery | Evaluate whether there is a difference between SAP block and SPSIP block at 12 hours after surgery at rest measure with visual analogic scale (0-10) |
| Pain at 24hours after surgery | 24 hours after surgery | Evaluate whether there is a difference between SAP block and SPSIP block at 24 hours after surgery at rest measure with visual analogic scale (0-10) |
| Pain at 6 hours after surgery | 6 hours after surgery | Evaluate whether there is a difference between SAP block and SPSIP block at 6 hours after surgery at rest measure with visual analogic scale (0-10) |
| Postoperative Opioid consumption | From extubation to 24 hours post-enrollment | Postoperative use of rescue analgesics (measured as yes or no) |
| Postoperative Nausea and Vomiting | From extubation to 24 hours post-enrollment | Postoperative Nausea and Vomiting defined as patient reporting nausea and vomiting or requiring drugs for nausea or vomiting |
| Intraoperative Opioid consumption | During the surgery(From patient intubation to patient extubation) | Intraoperative opioids consumption (remifentanyl measured as mcg/kg) |
Contacts
Primary ContactValentina Scaduto
Outcome results
None listed