Hypoxia
Conditions
Keywords
High flow nasal cannula oxygen
Brief summary
During painless gastroscopy, the occurrence of hypoxia is a critical concern, especially under intravenous anesthesia using propofol. This study aimed to investigate the incidence of hypoxia during painless gastroscopy and evaluate preventive measures.
Detailed description
From June 15 th 2023 to August 15th 2023, 900 patients who underwent elective gastroscopy in the Renji Hospital, Shanghai Jiao Tong University School of Medicine were selected. They were divided into the high flow nasal cannula oxygen group and the conventional nasal cannula oxygen group by oxygen inhalation. Patient demographics, Mallampati class, and other relevant factors were compared between the two groups. Primary outcomes included the incidence hypoxia (SpO2 \< 90%), while secondary outcomes included subclinical respiratory depression, and adverse events related to nasal oxygen cannula.
Interventions
None listed
Sponsors
Fengli Liu
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
： * Patients aged 18 to 70 * Undergoing painless gastroscopy under intravenous anesthesia
Exclusion criteria
： * Severe respiratory disease * History of nasal bleeding or mucosal injury * Emergency cases * Pregnant or lactating female
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| incidence of hypoxia | 60 seconds | SpO2 levels less than 90% |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the incidence of subclinical respiratory depression and adverse events | 30 minute | the incidence of and subclinical respiratory depression (SpO2 levels between 90% and less than 95%) and adverse events(mouth or nasal dryness, headache, nasal mucosal injury with bleeding, barotrauma. ) |
Countries
China
Outcome results
None listed