Postoperative Analgesia, Pain Management, PCNL, Regional Anesthesia Block
Conditions
Keywords
Postoperative, Analgesia, Pain, Erector Spinae, Retrolaminar, Block, PCNL
Brief summary
The study will investigate the effects of ultrasound-guided ESPB and RLB on intraoperative and postoperative analgesia in patients undergoing PCNL to identify a safe and effective regional block method for postoperative analgesia
Detailed description
All the patients will be blinded to the intervention received in this study. All patients will receive standard general anesthesia technique with endotracheal intubation and muscle paralysis. Postoperatively, all patients will receive analgesia in the form of non-steroidal anti-inflammatory drugs and paracetamol. In case the VAS scores exceeded 4 in any group, the patients will receive rescue analgesia with 25 mg IV meperidine. In both groups, the ESPB and RLB will be performed after induction of general anesthesia using portable ultrasound device.
Interventions
ESPB
PROCEDUREultrasound-guided retrolaminar plane block
RLB
Sponsors
Alexandria University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
No
Inclusion criteria
\- Patients scheduled for PCNL
Exclusion criteria
* daily consumption of analgesics * allergy to local anesthetics * liver dysfunction * infection or previous surgery in the vertebral region. * patient refusal * pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measurement of visual analogue score | after the surgery average 48 hours postoperative | measurement of visual analogue score during rest and movement. The Score range from 0-10. 0 means no pain and 10 indicates the worst pain ever |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| postoperative additional analgesic requirement | after the surgery average 48 hours postoperative | Total cumulative analgesic requirement dose |
| assessing the patient satisfaction by a the short assessment of patient satisfaction score (SAPS) | after the surgery average 48 hours postoperative | from 0 to 28, where 0 is so dissatisfied and 28 means very satisfied |
| Time to ambulate | after the surgery average 12 hours postoperative | Time from discharge from the operating theatre to start to ambulate |
| presence of postoperative nausea and vomiting | after the surgery average 48 hours postoperative | Number of postoperative nausea and vomiting |
Countries
Egypt
Outcome results
None listed