Pain Management After Surgery
Conditions
Keywords
pediatric, thoracoscopic surgery, pain control, lidocaine
Brief summary
This study aims to investigate the efficacy of intraoperative intravenous lidocaine infusion on postoperative pain management and recovery in pediatric patients undergoing thoracoscopic pulmonary resection.
Interventions
DRUGLidocaine (drug)
a single bolus dose of lidocaine 1.5 mg/kg is administered concurrently with the induction of anesthesia, followed by a continuous infusion of lidocaine at a rate of 1.5 mg/kg/hr.
Continuous infusion of normal saline in the same volume as that administered to the lidocaine group.
Sponsors
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
6 Months to 7 Years
Healthy volunteers
No
Inclusion criteria
* Pediatric patients aged under 7 years undergoing thoracoscopic pulmonary resection
Exclusion criteria
* cardiac dysfunction requiring vasopressors or inotropic agents * atrioventricular block or bradycardia * Liver or kidney dysfunction * Hypersensitivity to local anesthetics
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| FLACC (ace, Legs, Activity, Cry, Consolability scale) Score | up to 1 hour after surgery | Highest FLACC Score recorded in the postanesthesia care unit (The scale is scored in a range of 0-10 with 0 representing no pain.) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Remifentanil dose | throughout surgery (up to 3 hours) | Total amount of remifentanil administered during surgery |
| ANI (Analgesia Nociception Index) | throughout surgery (up to 3 hours) | ANI (Analgesia Nociception Index) values during surgery (scale ranging from 0 (indicating maximum pain) to 100 (indicating no pain)) |
| FLACC scores | 6 hours, 12 hours, and 24 hours postoperatively | FLACC scores at 6 hours, 12 hours, and 24 hours postoperatively |
| Total analgesic dosage administered postoperatively | up to 3 days after surgery | — |
| Postoperative complications | until discharge (up to 3-4 days after surgery) | — |
Countries
South Korea
Contacts
Primary ContactJi-Hyun Lee, MD, PhD
Outcome results
None listed