Cerebral Palsy (CP)
Conditions
Keywords
Navigation skills, EEG, Virtual Reality, Cerebral Palsy
Brief summary
The goal of this study is to investigate the neural mechanisms that undergoes spatial navigation skills in children/adolescents aged between 8 and 17 years. These skills play an important role in daily life, as they allow us to orient ourselves in familiar and unfamiliar environments, locate objects, interact with them and memorize their position. Navigation abilities vary widely between individuals, change with age and might be affected by diseases, such as the cerebral palsy (CP). Previous studies have, in fact, demonstrated differences in the learning and adaptation methods of spatial navigation skills in children affected by CP compared to typically developing (TD) peers. Through the use of the electroencephalogram (EEG) we want to shed light on the mechanisms that govern this ability with the aim of: 1. better characterize spatial navigation skills in children/adolescents, both TD and affected by CP; 2. investigate the origin of the differences found between the spatial navigation skills of TD children and those affected by CP, improving knowledge of the pathology and thus allowing, in the future, to identify more adequate rehabilitation interventions.
Interventions
OTHERPreliminary assessment
Evaluation of the cognitive level through the Raven test and of spatial navigation skills through the Corsi test and the maze sub-test of the WISC-III.
OTHERNavigation task with EEG recording
Administration of the navigation task in an immersive virtual reality environment and EEG signal recording. The participant will wear virtual reality viewers and EEG cap. The task consists in moving and orienting themselves inside a five-way maze in order to reach a treasure. The participant will be asked to carry out 30 trials lasting a maximum of 120s each.
Sponsors
IRCCS Eugenio Medea
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
8 Years to 17 Years
Healthy volunteers
Yes
Inclusion criteria
* typically developing subjects aged between 8 and 17 years; * subjects with CP aged between 8 and 17 years;
Exclusion criteria
* subjects aged under 8 or over 17 years; * subjects with epileptic problems; * subjects with poor head control; * subjects with visual problems that can not be corrected with prescription lens;
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Power Spectral Density (PSD) | Once | Differences in power values between TD and CP subjects |
| Navigation performance | Once | Navigation performance based on the following parameters: number of routes visited in each trial; total length of the path for each trial; error between distance traveled and ideal distance for each trial (identified as the minimum distance to reach the treasure from the starting point); angle of rotation of the viewer in each trial; duration of each trial. |
Countries
Italy
Contacts
Primary ContactEmilia Biffi
Outcome results
None listed