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Chemical and Microbiological Exposure of Women on Dairy Cattle Farms

Expositions Chimique et Microbiologique Des Femmes Dans Les Exploitations Bovines laitières

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06709989
Acronym
DAISY-Expo
Enrollment
80
Registered
2024-11-29
Start date
2025-01-03
Completion date
2028-01-01
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Occupational Exposure to Chemicals

Keywords

farmer, women, occupational exposure, chemicals, pesticides, biocides

Brief summary

Although professionals working on dairy cattle farms come into contact with a wide range of chemicals and microbiological agents, little is known about this possible exposure, which occurs a priori via inhalation and skin contact. The aim of this research is to gain a better understanding of this chemical and microbiological exposure, and this research focuses in particular on professional women working on dairy cattle farms , who may be in charge of specific activities not commonly carried out by professional men. Exposure to pesticides, antiparasitic products and disinfectants will be the first substances to be investigated, followed by other chemical or particulate compounds present in everyday and professional environments. Exposure to these compounds will be measured by their presence in the urine, feces (if possible) and hair of around 60 participating women, as well as in bovine tuft/head hair and, if possible, air samples taken in milking buildings.

Interventions

None listed

Sponsors

Institut National de la Santé Et de la Recherche Médicale, France
Lead SponsorOTHER_GOV
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
CollaboratorOTHER
Ecole des Hautes Etudes en Santé Publique
CollaboratorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Adult woman working on a dairy cattle farm in the "Grand Ouest" region of France * Woman who speaks and understands French

Exclusion criteria

* working less than 20h/week in dairy farms * Woman under legal protection * unsigned consent form

Design outcomes

Primary

MeasureTime frameDescription
Exposure to chemicals of women working on dairy farmsAt inclusion and at the end of the follow-up (for hair-concentrations), and during specific periods of agricultural activities (with two 4-day periods of urine sample collection, one period of faeces collection, and one week of environmental sampling)Concentrations of pesticide molecules, biocides, disinfectants and microbiological agents, measured in * urines of professional women working on dairy farms, * the hair of professional women working on dairy farms, * faeces of professional women from dairy farms, * tuft/head hair from females in the herd on farms where female professionals work, * environmental samples of pesticide molecules (PPPs, pesticides), biocides, disinfectants and microbiological agents.

Secondary

MeasureTime frameDescription
Exposure to other chemicalsAt inclusion and at the end of the follow-up (for hair-concentrations), and during specific periods of agricultural activities (with two 4-day periods of urine sample collection, one period of faeces collection, and one week of environmental sampling)Concentrations measured in urine, hair, feces, toupillon/head hair and environmental samples from the farm of other chemical compounds present in the participants' professional uses and environments.

Countries

France

Contacts

PRINCIPAL_INVESTIGATORCecile Chevrier

Inserm UMR1085 Irset

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 10, 2026