Meningioma and Embolism Thrombosis Risk & Investigation of Coagulation

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06709833

Acronym

001_2024_BO2

Enrollment

100

Registered

2024-11-29

Start date

2024-12-16

Completion date

2026-08-31

Last updated

2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meningeoma, Surgical Resection, Thrombembolism

Keywords

meningeoma, thrombembolism, tissue-factor

Brief summary

Despite being generally benign tumors, meningiomas are associated with an increased risk for thrombembolic complications after surgical resection. The molecular mechanisms underlying this circumstance are still unknown. In this prospective observational trial, the investigators aim to evaluate the changes in coagulation and platelet function caused by tumor resection. Blood samples are obtained by patients undergoing meningioma resection before and immediately after resection to detect said changes. As a control cohort, blood samples are obtained from patients undergoing resection for glioma.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Patients undergoing resection for meningioma or * Patients undergoing resection for glioma or * Healthy controls * written consent for study participation

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
Tissue factor	duration of surfical tumor resection (a few hours)	Concentration of tissue factor at pre-surgery and immediately after tumor resection (during close-up).

Countries

Germany

Contacts

Primary ContactMichael Koeppen, MD

michael.koeppen@med.uni-tuebingen.de+4970712986935

Backup ContactAlice Bernard, MD

alice.bernard@med.uni-tuebingen.de+4970712968028

Outcome results