Colon Cancer
Conditions
Keywords
right side colon cancer, complete mesentery resection
Brief summary
The study was conducted on patients with advanced right-sided colon cancer, and the clinical pathological and prognostic data of the patients were compared between the two groups of patients who were randomly divided into those undergoing SMV and SMA left resection, with the aim of resolving the controversy over the left resection boundary of CME/D3 lymph node dissection through this study, and to clarify whether SMA left resection is superior to SMV left resection.
Interventions
PROCEDURESMA lymph node dissection
The lymph node dissection boundary is on the left side of the superior mesenteric artery (SMA)
PROCEDURESMV lymph node dissection
The lymph node dissection boundary is on the left side of the superior mesenteric vein (SMV)
Sponsors
Jiangxi Provincial Cancer Hospital
Jiangsu Cancer Institute & Hospital
Liaoning Cancer Hospital & Institute
The First Affiliated Hospital of Soochow University
Shanxi Province Cancer Hospital
The First Affiliated Hospital of Shanxi Medical University
Shaoxing People's Hospital
Shaoxing Second Hospital
Ningbo No. 1 Hospital
Ningbo No.2 Hospital
Jinhua Central Hospital
Affiliated Hospital of Jiaxing University
The First People's Hospital of Huzhou
The Central Hospital of Lishui City
Lishui Country People's Hospital
Zhejiang University
Yuyao People's Hospital
The Third Affiliated Hospital of Wenzhou Medical University
First Affiliated Hospital of Wenzhou Medical University
Cancer Hospital of Guangxi Medical University
Ningbo Medical Center Lihuili Hospital
Ruijin Hospital
Second Affiliated Hospital of Wenzhou Medical University
First Affiliated Hospital of Zhejiang University
Second Affiliated Hospital, School of Medicine, Zhejiang University
Shanghai Cancer Hospital, China
The Affiliated Tumor Hospital of Harbin Medical University
Shanghai 10th People's Hospital
The Second Affiliated Hospital of Harbin Medical University
Xiangshan No.1 People' s Hospital
Zhejiang Province People's Hospital
Sir Run Run Shaw Hospital
Sun Yat-sen University Cancer Hosptial
Haixing Ju, MD
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 78 Years
Healthy volunteers
No
Inclusion criteria
* right side colon cancer(The primary lesion is located in the ileocecal region, ascending colon, hepatic flexure of colon, or proximal transverse colon) * T3-4 and/or N1-2M0 * Colonoscopy and pathological biopsy confirmed colon adenocarcinoma
Exclusion criteria
* T1-2N0M0 * Cannot undergo curative resection * Simultaneous multiple primary colorectal cancer or other diseases requiring segmental resection * Distant metastasis * Tumor invades surrounding organs, requiring joint organ resection * Emergency surgery is required for complications such as intestinal obstruction, perforation, and bleeding * Patients who have received neoadjuvant therapy before surgery * Pregnant or lactating women * Patients who are not suitable or unable to tolerate surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 3 year DFS | 3 years | 3 year disease free survival |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 5 year OS | 5 years | 5 year Overall survival |
Countries
China
Outcome results
None listed