Antibiotics, Botriomycoma, Central Line, Home Parenteral Nutrition, Infection, Intestinal Failure, Sepsis
Conditions
Brief summary
Botriomycomas are frequent benign tumors in children. Their appearance on the central catheter orifice is a known event in clinical practice, but one that has been little studied. This lesion could lead to changes in pathways and an increase in the number of sepsis events, which would promote thrombosis and thus depletion of venous capital in patients who have been dependent on a central line for many years. This study is a pilot study which will enable us to better identify the risk factors for the development of such a tumour, and to take stock of the different treatments used and their respective efficacy.
Interventions
None listed
Sponsors
Hospices Civils de Lyon
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No
Inclusion criteria
* home parenteral nutrition patients * never diagnosed with an episode of botriomycoma on their central line * 0 to 18 years of age at diagnosis
Exclusion criteria
* Botriomycoma more than 10 years old at time of data collection (or lack of data) * Patient over 18 years of age * Not on home parenteral nutrition patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Appearance of Botryomycoma | From first diagnosis through a follow-up period of 2 years. | genetic characteristics (origin, phototype), local factors (mechanical, infectious), and general factors (history of sepsis). |
| Recurrence of Botryomycoma | From first diagnosis through a follow-up period of 2 years. | analyze risk factors for recurrence and evolution under different treatments. |
Countries
France
Outcome results
None listed