Meniscus Lesion, Osteoarthritis
Conditions
Keywords
posterior meniscus root lesion;Osteoarthrotis
Brief summary
Medial meniscus posterior root tears (MMPRT) account for 20% or more of all meniscus tears, but the diagnosis and treatment of this condition continues to plague the general population due to the complexity of the diagnosis and uncertainty of the treatment. Early as well as timely diagnosis and treatment is one of the effective ways to avoid accelerated knee degeneration. Based on this study, our team is going to conduct a clinical study on posterior medial meniscus tear, combining Magnetic Resonance Imaging(MRI) to dynamically assess the changes of meniscus and articular cartilage surface after the injury, and selecting a specific patient group to carry out different therapeutic interventions, which mainly include conservative treatment, partial meniscectomy, and meniscal repair, in order to clarify the effects of different treatment modalities on the articular cartilage after the posterior meniscus tear, and to help to delay the degeneration of knee joints. This is to clarify the effects of different treatment modalities on the articular cartilage after posterior medial meniscus tears and to provide appropriate advice for delaying the progression of osteoarthritis of the knee.
Interventions
PROCEDUREArthroscopic meniscus surgery
Comparison of the incidence of osteoarthritis with conservative treatment as well as arthroscopic partial resection as well as arthroscopic repair surgery for a condition known as posterior meniscus root injury.
Sponsors
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
50 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
1. Clinical diagnosis of posterior root tear of the medial meniscus; 2. Patients with K-L classification ≤ grade II; 3. The age range of 50-65 years old; 4. International Cartilage Repair Society (ICRS) Modified Magnetic Resonance Imaging Grading System ≤ Grade 2; 5. International Cartilage Repair Society (ICRS) arthroscopic grading system ≤ grade 2; 6. Knee joint mobility ≥90°; 7. Inversion deformity ≤10°; 8. Must be able to complete follow-up MRI within 2 years after knee meniscus surgery; 9. Must be able to complete clinical data;
Exclusion criteria
1. Can not participate in this study; 2. Patients with concomitant meniscal injuries elsewhere; 3. knee joint infection disease; 4. Osteoporosis disease; 5. Patients with previous history of knee surgery; 6. Knee joint instability disease; 7. Severe KOA disease; 8. Can not cooperate with MRI detection; 9. Cannot tolerate the surgery; 10. Those who cannot tolerate the arthroscopic knee surgery; 11. Neuromuscular system pathology disease;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of KOA | 30th November 2024 -30th November 2027 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Articular cartilage T2-mapping value | 30th November 2024 -30th November 2027 | Articular cartilage T2 mapping values, post-standardised range 0-1 |
Other
| Measure | Time frame | Description |
|---|---|---|
| VAS (visual analogue scale)，VAS score | 30th November 2024 -30th November 2027 | The specific scoring method is to draw a 10 cm horizontal line on top of the paper, with 0 at one end of the line indicating no pain, 10 at the other end indicating severe pain, and the middle portion indicating varying degrees of pain. |
| Lysholm score | 30th November 2024 -30th November 2027 | The score consists of eight indicators: pain (25 points), instability (25 points), atresia (15 points), swelling (10 points), limp (5 points), stair climbing (10 points), squatting posture (5 points), and the use of supports (5 points), with a total score of 100, with higher scores representing better knee function. 95 points or more is considered excellent, 94-85 points is good, 84-65 points is fair, and less than 65 points is poor. A score of less than 65 is poor. |
| HSS (Hospital for Special Surgery) Score | 30th November 2024 -30th November 2027 | The score is out of 100 and consists of pain (30 points), function (22 points including walking and stair climbing), knee mobility (18 points), muscle strength (10 points), flexion deformity (10 points), joint stability (10 points), and deductions (-5 points). The higher the score, the better the knee function. |
Contacts
Primary ContactHaifeng Zhang, Ph.D
Backup ContactYinxian Yu, Ph.D
Outcome results
None listed