Renal Transplantation
Conditions
Brief summary
The aim of this study was to compare respiratory function, muscle oxygenation, functional capacity, peripheral muscle strength, body composition, and frailty in kidney transplant recipients with and without inspiratory muscle weakness.
Interventions
None listed
Sponsors
Hacettepe University
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patients with kidney transplantation * At least 6 months after the kidney transplant * Not having regular exercise habits * Voluntary participation in the study
Exclusion criteria
* Having a musculoskeletal problem that may interfere with the tests * Having neurological impairment * Having chronic lung disease * Having had any cardiovascular event in the last 6 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Respiratory muscle strength | 1st day | Maximal inspiratory pressure (MIP) will be measured using a portable mouth pressure measuring device. |
| Functional capacity | 1st day | Will be evaluated with 6 minute walk test. |
| Peripheral muscle strength | 1st day | Knee extensor strength will be measured using a hand dynamometer. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Peak expiratory flow | 1st day | Respiratory function will be evaluated using spirometry. Peak expiratory flow will be recorded. |
| Forced mid-expiratory flow | 1st day | Respiratory function will be evaluated using spirometry. Forced mid-expiratory flow (FEF25-75) will be recorded. |
| Forced expiratory volume in one second | 1st day | Respiratory function will be evaluated using spirometry. Forced expiratory volume in one second will be recorded. |
| Fragility | 1st day | It will be assessed according to the criteria defined by Fried. The existence of 5 parameters is questioned here. These parameters are as follows: weight loss, weakness, fatigue, slowness, low physical activity. Those with 3 or more of the 5 identified components are classified as fragile. |
| Body composition | 1st day | It will be evaluated by bioelectrical impedance analysis method. Percentage of fat and lean body mass wiil be recorded. |
| Forced vital capacity | 1st day | Respiratory function will be evaluated using spirometry. Forced vital capacity will be recorded. |
| Forced expiratory volume in one second/forced vital capacity | 1st day | Respiratory function will be evaluated using spirometry. Forced expiratory volume in one second/forced vital capacity will be recorded. |
Countries
Turkey (Türkiye)
Contacts
Primary ContactMerve Firat
Backup ContactNaciye Vardar-Yagli
Outcome results
None listed