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Short, Animated Storytelling (SAS) for Addiction Stigma Reduction

Short, Animated Storytelling Video to Reduce Addiction Stigma: Protocol for a Multi-country, Online, Randomized, Controlled Trial With 13,500 Participants

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06705205
Acronym
SAS
Enrollment
13397
Registered
2024-11-26
Start date
2025-07-03
Completion date
2025-08-22
Last updated
2025-09-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Social Stigma Towards People With Addiction

Brief summary

Stigma towards people with addiction is a well-documented problem that negatively impacts help-seeking, treatment and recovery. Social contact with people recovering from addiction can promote empathy and reduce stigma, but social contact is difficult to scale. Short, animated storytelling (SAS) is a novel health communication approach that scales easily because it can leapfrog barriers associated with language, culture, literacy and education levels. This study will investigate if a SAS video intervention can be used to reduce stigma, boost optimism and hope, and increasing empathy towards people with addiction. The study will also explore mechanisms of action of SAS interventions, by measuring the contribution of sound design to the effect of the intervention.

Interventions

OTHERSAS video

The intervention is a short, animated storytelling video, with soundtrack, aimed at reducing addiction stigma.

Sponsors

Alexander von Humboldt Association
CollaboratorOTHER
Stanford Center for Digital Health
CollaboratorUNKNOWN
Stanford University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 49 Years
Healthy volunteers
Yes

Inclusion criteria

* Adults with basic English proficiency between the ages of 18-49

Exclusion criteria

* None

Design outcomes

Primary

MeasureTime frameDescription
Change in Addiction Stigma Scale Score as measured by the Attribution Questionnaire (AQ)Immediately post-intervention on Day 1 and after two weeksParticipants complete an 18-item shortened version of the validated AQ. The AQ-18 will be scored along a 9-point Likert scale indicating the extent to which participants agree with the item ranging from not at all to very much with a maximum score of 27 for each 3-item construct. Higher scores indicate greater stigma.

Secondary

MeasureTime frameDescription
Change in Optimism Scale ScoreImmediately post-intervention on Day 1 and after two weeksParticipants complete the Brief García's Interactive Optimism Scale (BIOS-G). The BIOS-G is an instrument designed to assess an individual's level of general optimism towards their life and other people. The scale includes 4 statements for which respondents indicate their level of agreement from 1 (Of course not) to 4 (Yes, of course). Higher scores indicate a greater level of optimism.
Change in Attitude Thermometer ScoreImmediately post-intervention on Day 1 and after two weeksParticipants will indicate their warmth towards subject using a self-report stigma thermometer. Using a scale scores from zero to 100, with higher scores indicating more empathy or more favorable attitudes.
Change in Levels of Hope using a visual analogue scale (VAS)Immediately post-intervention on Day 1 and after two weeksParticipants self-report levels of hope using a VAS, a longstanding, validated tool for assessing related constructs of stress and subjective well-being. The scale goes from zero to 100 and higher scores indicate higher levels of hope.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026