High Flow Nasal Cannula Compared to Standard Oxygen for Endoscopic Ultrasound

High Flow Nasal Cannula Compared to Standard Oxygen Therapy for Endoscopic Ultrasound Procedure in High Risk Patients on Recovery Time and Procedural Conditions

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06704867

Enrollment

200

Registered

2024-11-26

Start date

2025-07-14

Completion date

2027-02-01

Last updated

2026-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endoscopic Ultrasound

Keywords

High Flow Nasal Cannula, High BMI, Oxygen

Brief summary

The purpose of the study is to evaluate the use of high flow nasal cannula versus standard oxygen therapy for high-risk patients undergoing endoscopy procedures.

Detailed description

Patients with a higher BMI are at greater risk for lower oxygen levels which can delay the endoscopy procedure. This research is being conducted to find out if high risk patients will have a shorter recovery time and improved procedural conditions with a high flow nasal cannula versus standard oxygen therapy.

Interventions

OTHERHigh flow nasal cannula

Subjects undergoing endoscopic ultrasound will receive high flow nasal cannula during the procedure

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Caregiver)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

• All patients age 18 years and older who present to Gonda 2 procedural area for Endoscopic ultrasound (EUS) with or without endoscopy (EGD)/biopsy/tissue sampling. with BMI ≥ 35 kg/m2 (BMI within the past 6 months in electronic medical records or at current procedure) who are able to consent will be approached for potential enrollment.

Exclusion criteria

* Need for general anesthesia for the procedure instead of the standard monitored anesthesia care. * Patients undergoing combined procedure: Therapeutic EUS/combined procedures including EUS/ERCP, EUS/colonoscopy * Patients on home oxygen therapy, or the diagnosis of "severe COPD" * Patients with existing tracheostomy * Inpatients undergoing EUS * Inability to consent * Cognitive impairment * Blocked nasal passages * Trauma/previous surgery to the nasopharynx * Irregularities of the nose, face, or airway such that HFNC cannot be properly fitted

Design outcomes

Primary

Measure	Time frame	Description
Decrease recovery time	4 hours	Time measured in minutes for participants to enter post anesthesia care until the nurse marks "ready for discharge" in the medical record.

Secondary

Measure	Time frame	Description
Improve procedural conditions	1 hour	Decreased number of times the procedure is paused or delayed.

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORBhargavi Gali, MD, MHA

Mayo Clinic

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 9, 2026